Objective To explore the difference of diagnostic efficacy between computed tomography(CT)and magnetic resonance imaging(MRI)in cerebral blood vessels and cerebral perfusion in patients with acute cerebral infarction.Methods 76 patients with acute cerebral infarction from February 2020 to April 2022 in our hospital were selected as the study subjects by a prospective study.All patients underwent CT angiography(CTA),CT perfusion(CTP),MRI(including high-resolution cube T1WI,multi delayed pseudo continuous arterial spin labeling(pCASL)]and digital subtraction angiography(DSA).Taking the results of DSA as the gold standard,the difference between MRI related examinations and CTA in the diagnosis of cerebral vascular stenosis in patients with acute cerebral infarction were analyzed,and the consistency of CTA,MRI and DSA diagnostic results by Kappa value were expressed.The relevant perfusion parameters cerebral blood flow(CBF)were obtained from the multi delayed pCASL examination,and the CBF and mean transit time(MTT)were obtained from the CTP examination.The Pearson correlation coefficient differences between the multi delayed pCASL and CTP perfusion parameters in gray matter,white matter and whole brain regions were compared on the basis of voxel level.Results Taking DSA results as the gold standard,69 of 76 patients with acute cerebral infarction were found to have stenosis of different degrees after MRI,CT and DSA.Compared with the results of DSA,the stenosis degree of 4 patients was high in cube T1WI,1 patient was low,5 patients were high in CTA,and 3 patients were low.Compared with the results of the three diagnostic methods,Kappa values were all in the range of 0.800-1.000,with high consistency(P<0.05).The CBF values of pCASL were(25.63±12.17)mL/(100 g·min),(39.78±17.53)mL/(100 g·min),(32.64±15.12)mL/(100g·min)when PLD was 1 500 ms,1 800 ms and 2 500 ms,respectively.The CBF value obtained by pCASL was significantly positively correlated with the CBF value obtained by CTP and MTT treatment at the PLD of 1 500 ms,1 800 ms and 2 500 ms(P<0.05).Conclusion In the evaluation of cerebrovascular and cerebral perfusion in patients with acute cerebral infarction,CT and MRI have better diagnostic efficacy,but cube T1WI and DSA have higher consistency in cerebrovascular diagnosis,and the safety of multi delayed pCASL perfusion is better.