首页|胸痛救治单元对急性ST段抬高型心肌梗死救治关键时间节点及短期预后的影响

胸痛救治单元对急性ST段抬高型心肌梗死救治关键时间节点及短期预后的影响

The impact of chest pain treatment unit on the key time points for the treatment of acute ST-segment elevation myocardial infarction and short-term prognosis

扫码查看
目的 通过对胸痛中心数据库的回顾性调查研究,分析胸痛中心建设中胸痛救治单元选择三绕行(绕行胸痛救治单元、急诊科、心脏重症监护室)策略对急性ST段抬高型心肌梗死(STEMI)患者救治关键时间节点及短期预后的影响.方法 选取 2019 年 10 月—2023 年 9 月间苍南县胸痛中心收治的STEMI患者,根据患者属地是否建设胸痛救治单元,主导选择三绕行直达数字减影血管造影(DSA)室行直接经皮冠状动脉介入治疗(PPCI),分为观察组和对照组,分析收治的STEMI患者的一般资料及不同来院方式、发病至首次医疗接触(SO-to-FMC)时间、首份心电图完成时间、床旁肌钙蛋白完成时间、再灌注知情同意时间、入门至导丝通过(D-to-W)时间等关键时间节点及住院日、住院总费用、住院期间左心室射血分数(LVEF)、心力衰竭发生率、30d病死率、3 个月病死率等,比较两组间指标差异.结果 该研究数据库共纳入 319 例STEMI患者,两组均男性明显多于女性、年龄均数无明显差异、均以自行来院方式为主,两组的呼叫 120、转院、自行来院的数量和占比差异有统计学意义(χ2=5.613、4.972、5.144,P<0.05).两组间SO-to-FMC、首份心电图、D-to-W、知情同意谈话时间差异有统计学意义(t=3.033、4.974、4.362、4.079,P<0.05),肌钙蛋白时间和导管激活时间无统计学差异(P>0.05).拒绝PPCI的例数和占比,观察组明显少于对照组,差异有统计学意义(χ2=5.107,P<0.05);观察组的住院日及总费用较对照组有明显减少,差异有统计学意义(t=3.444、2.357,P<0.05).观察组住院期间LVEF高于对照组,心力衰竭发生率、30d和 3 个月病死率明显少于对照组,差异有统计学意义(t=5.673,χ2=3.134、3.201、4.019,P<0.05).结论 胸痛救治单元建设要求选择三绕行直达DSA行PPCI,通过选择正确的来院方式,缩短SO-to-FMC时间、首份心电图时间、D-to-W时间、知情同意时间等关键时间节点,从而缩短STEMI患者的总缺血时间,提高住院期间的左心室射血分数,降低心力衰竭发生率,减少住院日、住院总费用,降低 30d和 3 个月病死率,从而改善STEMI患者的短期预后.
Objective To analyze the impact of the three bypassing strategies(bypassing chest pain treatment unit,emergency department,and Cardiac Care Unit)selected in chest pain center construction on the critical time nodes and short-term prognosis of patients with acute ST-segment elevation myocardial infarction(STEMI)through a retrospective investigation of the chest pain center database.Methods Patients with STEMI admitted to the Cangnan County Chest Pain Center from October 2019 to September 2023 were selected.According to whether the patient′s hometown had a chest pain treatment unit,patients were mainly selected for emergency primary percutaneous coronary intervention(PPCI)through three bypass and Direct digital subtraction angiography(DSA)room,divided into observation group and control group.General data of STEMI patients,key time nodes such as arrival mode,time from symptom onset to first medical contact(SO-to-FMC),time from first ECG completion to bedside troponin completion,informed consent time for reperfusion,door-to-wire time(D-to-W),length of hospital stay,total hospitalization expenses,left ventricular ejection fraction(LVEF)during hospitalization,incidence of heart failure,30-day and 3-month case fatality rate were analyzed and compared between the two groups.Results A total of 319 STEMI patients were included in the study database.There were more male patients in both groups than female patients,and there was no significant difference in the mean age between the two groups.The self-arrival mode was mainly used in both groups,and there were differences in the numbers and proportions of patients who called 120,transferred,and self-arrived between the two groups,with statistically significant differences(χ2=5.613,4.972,5.144,P<0.05).There were significant differences in SO-to-FMC,ECG completion time,D-to-W,informed consent conversation time(t=3.033,4.974,4.362,4.079,P<0.05),and troponin time between the two groups,while there was no significant difference in the time of catheter activation(P>0.05).The proportion of cases rejected for PPCI in the observation group was significantly lower than that in the control group,with a statistically significant difference(χ2=5.107,P<0.05).The length of hospital stay and total hospitalization expenses in the observation group were significantly reduced compared with those in the control group(P<0.05).The LVEF during hospitalization in the observation group was higher than that in the control group,and the incidence of heart failure,30-day and 3-month case fatality rate were significantly lower than those in the control group(t=5.673,χ2=3.134,3.201,4.019,P<0.05).Conclusion The establishment of a chest pain treatment unit requires selecting three bypass strategies to perform PPCI.By selecting correct arrival methods,shortening SO-to-FMC time,ECG completion time,D-to-W time,informed consent conversation time,etc.,key time nodes can be shortened to reduce the total ischemic time of STEMI patients,improve LVEF during hospitalization,reduce the incidence of heart failure,reduce length of hospital stay and total hospitalization expenses,reduce 30-day and 3-month case fatality rate,thereby improving the short-term prognosis of STEMI patients.

Chest pain rescue unitAcute ST-segment elevation myocardial infarctionKey time nodesImpact factors

范兴恳、谢珊珊、杨桂香、谢尚利、张贻平、陈学秀、庄载受

展开 >

温州医科大学附属苍南医院急诊科,浙江苍南 325800

胸痛救治单元 急性ST段抬高型心肌梗死 关键时间节点 影响因素

2024

中国急救复苏与灾害医学杂志
中国医学救援学会

中国急救复苏与灾害医学杂志

CSTPCD
影响因子:0.568
ISSN:1673-6966
年,卷(期):2024.19(12)