首页|小探头超声内镜在小直径低级别直肠神经内分泌肿瘤内镜手术中的应用

小探头超声内镜在小直径低级别直肠神经内分泌肿瘤内镜手术中的应用

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目的 评价小探头超声内镜(EUS)指导小直径(最大直径小于1 cm)低级别(G1级)直肠神经内分泌肿瘤(R-NEN)治疗的应用价值,为其临床应用和进一步研究提供循证医学证据和线索.方法 回顾性分析2014年1月至2020年12月在本中心行内镜治疗的85例小直径低级别(G1级)R-NEN患者的临床资料,根据内镜治疗前是否行EUS检查将患者分为EUS组(37例)和对照组(48例).比较2组患者内镜治疗后的切缘阳性率、并发症发生率、复发率、住院时间、住院费用、内镜治疗方式等指标.结果 EUS组患者切缘阳性率显著低于对照组(P<0.05).2组患者并发症发生率、肿瘤复发率、住院时间及住院费用比较,差异均无统计学意义(P>0.05).2组患者内镜治疗方式比较,差异有统计学意义(P<0.05).结论 对小直径低级别(G1级)R-NEN术前进行小探头EUS检查评估病变深度,并根据其结果选择内镜手术方式,可明显降低切缘肿瘤的残留风险.
Application of miniprobe endoscopic ultrasound in endoscopic surgery of small-diameter and low-grade rectum neuroendocrine neoplasm
Objective To evaluate the value of miniprobe endoscopic ultrasound(EUS)in guiding endoscopic treatment of small-diameter(maximum diameter less than 1 cm)and low-grade(G1 grade)rectum neuroendocrine neoplasm(R-NEN),and to provide evidence and clues for its clinical application and further research.Methods The clinical data of 85 cases of low-grade(G1 grade)R-NEN with a maximum diameter of less than 1 cm who underwent endoscopic treatment in our center from January 2014 to December 2020 were retrospectively analyzed.The patients were divided into the EUS group(37 cases)and control group(48 cases)according to whether EUS was performed before endoscopic treatment.The positive rate of incision margin,the incidence of complications,the recurrence rate,the hospital stay,the cost of hospitalization and endoscopic therapy were compared between the two groups.Results The positive rate of incision margin in the EUS group was significantly lower than that in control group(P<0.05).There was no significant difference in the incidence of complications,tumor recurrence rate,hospital stay or hospital costs between the two groups(P>0.05).There was statistically significant difference in the endoscopic therapy between the two groups(P<0.05).Conclusion Evaluating the lesion depth of small-diameter and low-grade(G1 grade)R-NEN before surgery by miniprobe EUS and selecting endoscopic surgery according to its results of can significantly reduce the residual risk of resection margin tumors.

miniprobeendoscopic ultrasoundrectumneuroendocrine neoplasmprecision therapy

李建军、樊超强、杨歆、彭学、林昊、聂旭彪、杨仕明、谯秋建、柏健鹰

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陆军军医大学第二附属医院消化内科,重庆 400037

四川大学华西临床医学院,四川 成都 610041

小探头 超声内镜 直肠 神经内分泌肿瘤 精准治疗

重庆市卫生适宜技术推广项目

2017jstg30

2024

局解手术学杂志
重庆市解剖学会,第三军医大学

局解手术学杂志

CSTPCD
影响因子:1.063
ISSN:1672-5042
年,卷(期):2024.33(1)
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