Research progress on the mechanism of tranexamic acid improving coagulation function in patients with traumatic brain injury
Coagulation dysfunction after traumatic brain injury(TBI)is one of the important causes of secondary brain injury.Therefore,early assessment of the condition of TBI patients and improvement of clinical prognosis are particularly important for the diagnosis and intervention of coagulation dysfunction.As an anti-fibrinolytic agent,tranexamic acid(TXA)can inhibit the action of plasmin,demonstrate anti-fibrinolytic and hemostatic abilities,and thus improve coagulation function.This article reviews the mechanism of coagulation dysfunction after TBI and the mechanism of TXA action,in order to provide reference for clinical evaluation and treatment.
traumatic brain injurytranexamic acidcoagulation function
万方数据
维普
