Coagulation dysfunction after traumatic brain injury(TBI)is one of the important causes of secondary brain injury.Therefore,early assessment of the condition of TBI patients and improvement of clinical prognosis are particularly important for the diagnosis and intervention of coagulation dysfunction.As an anti-fibrinolytic agent,tranexamic acid(TXA)can inhibit the action of plasmin,demonstrate anti-fibrinolytic and hemostatic abilities,and thus improve coagulation function.This article reviews the mechanism of coagulation dysfunction after TBI and the mechanism of TXA action,in order to provide reference for clinical evaluation and treatment.
关键词
创伤性颅脑损伤/氨甲环酸/凝血功能
Key words
traumatic brain injury/tranexamic acid/coagulation function
维普
万方数据