首页|基层医院330例中毒患者洗胃现状和适应证分析

基层医院330例中毒患者洗胃现状和适应证分析

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目的 通过分析经消化道中毒患者的临床资料,评估患者洗胃是否具有适应证,并提出改进措施.方法 回顾性分析2019年1月1日至2022年12月31日南京医科大学第一附属医院江苏省人民医院(溧阳分院)收治的经消化道中毒患者的临床数据,比较洗胃和未洗胃两组患者数据,筛选毒物类型明确和记录中毒至洗胃时间的患者,根据毒性和间隔时间评估患者洗胃是否符合适应证.结果 共收集434例经消化道中毒患者,男性155例(35.7%),年龄中位数为52(28,72)岁,药物中毒占57.4%,农药中毒占36.4%,76.0%洗胃,32.3%应用特效解毒剂,9.9%进行机械通气.农药中毒较药物中毒洗胃比例更高(91.8%vs.69.5%,P<0.001).有明确毒物类型及中毒至洗胃时间的患者共273例,其中16.1%摄入危及生命的高毒物质,75.5%2 h内洗胃.依据毒性和摄入至洗胃时间,36.7%洗胃适应证较符合.比较2019~2021年和2022~2023年两个阶段,洗胃率下降,但差异无统计学意义(P>0.05),适应证符合情况下降,差异有统计学意义(P<0.05).结论 基层医院中毒洗胃率较高,大多数患者均在2 h内给予洗胃,适应证的符合率偏低.中毒患者是否洗胃应参考毒性、摄入至就诊时间和洗胃禁忌证.急诊医生应定期接受临床毒理学培训.
Clinical features and indications of 330 poisoning patients with gastric lavage in the primary hospital
Objective To assess whether poisoning patients with gastric lavage meet the indications and to propose improvement measures in poisoning treatment by analyzing the clinical data of patients with gastrointestinal poisoning.Methods The medical records of poisoning patients in Jiangsu Province Hospital(Liyang Branch),the First Affiliated Hospital of Nanjing Medical University from January 1,2019 to December 31,2022,were retrospectively analysed.The patients with definite poison types and recorded time from ingestion to gastric lavage were screened out.According to poison toxicity and the interval time,whether the patients met the indications of gastric lavage was evaluated.Results Of the 434 patients with gastrointestinal poisoning,there were 155 males(35.7%)with a median age of 52(28,72)years.Drug poisoning and pesticide poisoning accounted for 57.4%and 36.4%respectively.76.0%cases received gastric lavage,32.3%cases used specific antidotes and 9.9%cases underwent mechanical ventilation.The proportion of gastric lavage in pesticide poisoning was higher than that in drug poisoning(91.8%vs.69.5%,P<0.001).Of the 273 patients with definite poison types and the time from ingestion to gastric lavage,16.1%cases ingested life-threatening poisoning substances,75.5%cases received gastric lavage within 2 hours.Based on toxicity and the time from ingestion to gastric lavage,36.7%cases met the indications of gastric lavage.The frequency of gastric lavage fell from 2019-2021 to 2022-2023,but there was no stastical significance(P>0.05).The coincidence rate of indications was also decreased over the period,and there was significant difference(P<0.05).Conclusions At present,gastric lavage as poisoning treatment is still widely used in primary hospitals.The majority of poisoning patients received gastric lavage within 2 hours,but the coincidence rate of indications is low.Emergency doctors should refer to toxicity,the time from ingestion to visit and contraindications for gastric lavage to determine whether the poisoning patients need gastric lavage.Emergency doctors are encouraged to receive regular training of clinical toxicology.

PoisoningGastrointestinal decontaminationGastric lavageToxicity

徐铖、时育彤、朱轶、李天时、陈旭锋、黄培培

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210029 江苏南京,南京医科大学第一附属医院江苏省人民医院急诊与危重症医学科

213300 江苏溧阳,江苏省人民医院溧阳分院溧阳市人民医院急诊科

中毒 消化道毒物清除 洗胃 毒性

2025

中国急救医学
中国医师协会,黑龙江省科学技术情报研究所

中国急救医学

影响因子:1.868
ISSN:1002-1949
年,卷(期):2025.45(1)