首页|鸡生长性状相关SH3RF2、LncFAM及IGF2BP1基因SV变异的聚合效应分析

鸡生长性状相关SH3RF2、LncFAM及IGF2BP1基因SV变异的聚合效应分析

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试验旨在对生长性状大效应基因SH3RF2、LncFAM及IGF2BP1的3个突变位点进行聚合效应分析,选出最优组合基因型.试验以鸡7个群体(固始-安卡F2代资源种群、AA肉鸡、哈伯德肉鸡、科宝肉鸡、817肉鸡、广西金陵麻鸡和卢氏绿壳蛋鸡)中的2 228个个体为研究对象,检测三个基因位点的基因型变异,利用F2资源群和广西金陵麻鸡研究鸡SH3RF2、LncFAM及IGF2BP1基因的遗传效应,对三个基因组合位点的聚合效应进行分析.结果显示:在分析群体中共有54种可能的组合基因型,通过基因型频率和生长性状关联分析发现,在7个群体中,等位基因Sh-I、Lnc-I和Ig-L1的频率均明显高于Sh-D、Lnc-D、Ig-L2及Ig-W;在F2资源群体和广西金陵麻鸡中,IIIIL1L1基因型在三个基因聚合效应中具有较高的基因频率和较高的体重.结果表明,在提高生长性状方面,IIIIL1L1基因型既能提高体重,又有较高的基因型频率,可以作为选择推荐联合标记.
Analysis of Aggregation Effect of SV Variation of SH3RF2,LncFAM and IGF2BP1 Genes Related to Growth Traits in Chicken
The purpose of this study was to analyze the aggregation effect of three mutation loci of SH3RF2,LncFAM and IGF2BP1,which were large effect genes for growth traits,and to select the optimal combination genotype.In this study,2 228 indi-viduals from 7 chicken populations(Gushi-Anka F2 resource population,AA broiler,Hubbard broiler,Cobb broiler,817 broiler,Guangxi Jinling partridge chicken and Lushi green shell layer)were used to detect the genotypic variation of the three gene loci.Then,the genetic effects of SH3RF2,LncFAM and IGF2BP1 genes in F2 resource population and Guangxi Jinling partridge chick-en were used to analyze the aggregation effect of the three gene combination loci.The results showed that there were 54 possible combined genotypes in the analysis population.Through the correlation analysis of genotype frequency and growth traits,it was found that the frequencies of allele Sh-I,allele Lnc-I and allele Ig-L1 in the 7 populations were significantly higher than those of Sh-D,Lnc-D,Ig-L2 and Ig-W.In the F2 resource population and Guangxi Jinling partridge chicken,the IIIIL1L1 genotype had higher gene frequency and higher body weight in the three gene aggregation effects.The results showed that IIIIL1L1 genotype could not only increase body weight but also have a higher genotype frequency in terms of improving growth traits,which could be used as a selection recommendation for co-markers.

chickengrowth traitsSH3RF2 geneLncFAM geneIGF2BP1 genepyramiding effectassociation analysis

刘阳、马浩翔、王文韬、刘树立、唐燕飞、蒋华连、苏立燧、韩瑞丽、刘小军、田亚东、王香南、李转见

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河南农业大学动物科技学院,河南 郑州 450046

广西富凤农牧集团有限公司,广西 南宁 530000

河南省农业科学院畜牧研究所,河南 郑州 450002

生长性状 SH3RF2基因 LncFAM基因 IGF2BP1基因 聚合效应 关联分析

2025

中国家禽
中国畜牧业协会 中国农科院家禽研究所 江苏省家禽科学研究所

中国家禽

北大核心
影响因子:0.482
ISSN:1004-6364
年,卷(期):2025.47(1)