中国介入心脏病学杂志2024,Vol.32Issue(1) :51-57.DOI:10.3969/j.issn.1004-8812.2024.01.010

经导管主动脉瓣置换术相关脑卒中及脑栓塞保护装置研究进展

New advances in stroke and cerebral embolism protection devices in transcatheter aortic valve replacement

李云峰 周世强 史喜德 李飞
中国介入心脏病学杂志2024,Vol.32Issue(1) :51-57.DOI:10.3969/j.issn.1004-8812.2024.01.010

经导管主动脉瓣置换术相关脑卒中及脑栓塞保护装置研究进展

New advances in stroke and cerebral embolism protection devices in transcatheter aortic valve replacement

李云峰 1周世强 2史喜德 1李飞1
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作者信息

  • 1. 中国人民解放军空军军医大学第一附属医院心血管内科, 陕西西安 710032
  • 2. 中国人民解放军空军军医大学第一附属医院心血管内科, 陕西西安 710032;天水市第一人民医院心血管内科,甘肃天水 741000
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摘要

脑卒中作为经导管主动脉瓣置换术(TAVR)最严重并发症之一,显著增加患者神经认知功能下降和死亡的风险.随着TAVR的适应证进一步扩展到外科低风险患者群体,脑卒中的防治至关重要.近年来多种脑栓塞保护装置(CEPD)被用于过滤或偏转去往脑循环的栓塞碎片,已成为预防脑卒中的一种选择,因此亟需了解CEPD在预防脑卒中的作用及适用群体,然而,目前TAVR相关脑卒中的风险因素以及常规使用CEPD的证据尚存在争议.本文就TAVR相关脑卒中及CEPD的研究证据进行综述,并概述了这一领域的最新进展.

Abstract

Stroke is one of the most serious complications of transcatheter aortic valve replacement(TAVR),tremendously increasing mortality and the loss of neurocognitive function.Since TAVR is expected to further spread into lower-risk patient groups,there will be greater emphasis to obviate such serious complications.One possible technique for preventing stroke is using cerebral embolic protection devices(CEPDs).CEPDs are designed for capturing or deflecting emboli that are enter route to the brain and hence to protect the brain from embolism.Since this is a rapidly growing field with recent advances,and the impact of CEPD on preventing neurological events is still limited,there is an urgent need for understanding the role of CEPD in preventing clinically significant strokes.Although their clinical utilization is increasing,the risk factors for stroke related to TAVR and evidence for using CEPDs are not yet clear.In this review,we present an overview of the available literature on TAVR related stroke and CEPD,and outline recent advances within this field.

关键词

主动脉瓣狭窄/脑栓塞保护/脑卒中/经导管主动脉瓣置换术

Key words

Aortic stenosis/Cerebral embolic protection/Stroke/Transcatheter aortic valve replacement

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基金项目

国家自然科学基金(82170250)

出版年

2024
中国介入心脏病学杂志
北京大学

中国介入心脏病学杂志

CSTPCDCSCD
影响因子:1.224
ISSN:1004-8812
参考文献量48
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