中国介入心脏病学杂志2024,Vol.32Issue(2) :96-100.DOI:10.3969/j.issn.1004-8812.2024.02.006

冠状动脉微循环阻力指数的应用与进展

Application and progress of index of microcirculatory resistance

任凌彤 艾虎
中国介入心脏病学杂志2024,Vol.32Issue(2) :96-100.DOI:10.3969/j.issn.1004-8812.2024.02.006

冠状动脉微循环阻力指数的应用与进展

Application and progress of index of microcirculatory resistance

任凌彤 1艾虎1
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作者信息

  • 1. 北京医院心内科国家老年医学中心中国医学科学院老年医学研究院,北京 100730;北京大学医学部第五临床医学院,北京 100730
  • 折叠

摘要

随着对冠状动脉相关疾病研究的深入,人们逐渐认识到冠状动脉微循环障碍对于心血管疾病的发生、发展、疗效及预后等具有重要影响,冠状动脉微循环疾病在缺血性心脏病中受到越来越多的重视.由于无法直接通过影像学观察到冠状动脉微血管,目前临床上出现了一些评价冠状动脉微循环功能的指标,其中微循环阻力指数被广泛用于冠状动脉微循环功能评价.基于计算流体力学的微循环阻力指数测定技术准确、安全、简单易行,应用前景广泛.本文就微循环阻力指数的建立、发展、临床应用、进展进行综述.

Abstract

With the deepening of the research on coronary artery related diseases,people gradually realize that coronary microcirculation disorders have an important impact on the occurrence,development,curative effect and prognosis of cardiovascular diseases,and coronary microcirculation diseases have received more and more attention in ischemic heart disease.Since coronary microvessels cannot be directly observed through imaging,there are currently some indicators to evaluate coronary microcirculation function in clinical practice,among which the index of microcirculatory resistance(IMR)is widely used for the evaluation of coronary microcirculation function.Computational fluid dynamics derived IMR is accurate,easy to perform,and has a broad application prospect.This article provides a comprehensive review of the establishment,development,clinical applications,and progress of IMR.

关键词

微循环阻力指数/冠状动脉微循环功能障碍/计算流体力学

Key words

Index of microcirculatory resistance/Coronary microcirculation dysfunction/Computational fluid dynamics

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基金项目

中国医科院医学与健康科技创新工程项目(2021-I2M-C&T-A-019)

首都临床诊疗技术研究及转化应用项目(Z211100002921008)

中央高水平医院临床科研业务费项目(BJ-2019-193)

出版年

2024
中国介入心脏病学杂志
北京大学

中国介入心脏病学杂志

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影响因子:1.224
ISSN:1004-8812
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