Assessment of the quality of life of patients with echinococcosis in Gansu Province pre-and post-surgery based on the EQ-5D-5L questionnaire
Objective To analyse the changes in quality of life of patients with echinococcosis in Gansu Province pre-and post-surgery,and evaluate the impact of surgical treatments on the patients'quality of life.Meth-ods The patients with echinococcosis underwent surgery and were managed under the National Project for Echinococ-cosis Control and Prevention in Gansu Province were surveyed using questionnaire and EQ-5D-5L questionnaire to col-lect basic information,first visit record,surgical performance,and the quality of life pre-and post-surgery.The data were analyzed by SPSS 19.0 and Origin 2021.Results A total of 856 cases collected,including 417 males and 439 females.The age ranges from 7 to 85 years,with an average of 53 years.There were 737 cases of CE patients,14 cases of AE patients,and 105 cases of unclassified patients.The longest time from the first surgery to postoperative fol-low-up for patients with echinococcosis was 17.5 years,and the shortest was 1 month.The average time interval be-tween the investigation and the first surgery was 7.4 years(89 months).The preoperative and postoperative health utility values for patients with echinococcosis were 0.910±0.142 and 0.967±0.067,respectively,showing a 6.3％improvement postsurgery(Z=-12.081,P＜0.05).The preoperative and postoperative visual analog scale(VAS)scores were 79.10±16.00 and 86.25±11.64,respectively,showing a 9.0％improvement postsurgery(Z=-15.292,P＜0.05).The health utility value difference in patients with echinococcosis ranged between-0.308 and 1.348,the VAS score difference ranged be-tween-55 and 90.A total of 42.8％(366/856)patients had an increase in health utility value postsurgery,and 62.7％(537/856)of patients had an increase in VAS score postsurgery.The proportion of patients with reduction of difficulties in the five dimensions was 19.1％(818/4 280),unchanged was 76.5％(3 275/4 280),and those with stable overall health had higher health utility values(Z=-16.580,P＜0.05)and VAS scores(Z=-8.606,P＜0.05).The proportion of patients with increased difficulties was 4.4％(187/4 280),the average age of first operation in the group with de-creased health utility value was higher than that in another group(Z=4.393,P＜0.05).The average age of first opera-tion in the group with decreased VAS score was higher than that in another group(Z=3.154,P＜0.05).The patients'health utility value(F=12.957,Ptrend＜0.05)and VAS score(F=10.808,Ptrend＜0.05)showed a trend of positive linear correlation with the extension of postsurgery time.Conclusion Surgical treatment could impact the quality of life for patients with echinococcosis.
EchinococcosisEQ-5D-5L questionnaireSurgical patientsQuality of lifeGansu Province
NETL
NSTL
万方数据
