[Objective]To compare the clinical outcomes and complications of transforaminal lumbar interbody fusion(TLIF)versus oblique lateral interbody fusion(OLIF)combined with pedicle screw fixation through posterior intermuscular channel approaches for degen-erative diseases of the lumbar spine.[Methods]A retrospective study was conducted on 157 patients who underwent lumbar interbody fu-sion for lumbar degenerative diseases in our hospitals from January 2016 to December 2018.According to the doctor-patient communica-tion,81 patients received TLIF,while other 76 patients were treated with OLIF.The clinical documents,including complications,of the two groups were observed and compared.[Results]Although there were no significant differences in operation time and ambulation time between the two groups(P＞0.05),the OLIF groups proved significantly superior to the TLIF group in terms of intraoperative blood loss[(79.8±26.5)ml vs(258.2±49.9)ml,P＜0.05]and the hospital stay[(7.4±0.8)days vs(9.3±1.0)days,P＜0.05].With time of follow-up lasted for(20.8± 10.8)months on an average,the VAS scores for lower back pain and leg pain,as well as ODI score were significantly reduced in both groups(P＜0.05),which was not statistically significant between the two groups at any time points accordingly(P＞0.05).Radiologically,interverte-bral height,coronal and sagittal Cobb angle of lumbar spine significantly improved in both groups at the last follow-up compared with those preoperatively(P＜0.05),whereas which were statistically insignificant between the two groups at any time accordingly(P＞0.05).Regarding to complications,the OLIF group was significantly higher in term of early incidence than the TLIF group(34.2％vs 19.8％,P＜0.05),despite insignificant difference in late complication incidence between the two groups(1.3％vs 1.2％,P＞0.05).[Conclusion]The incidence and composition of complications are different between the two lumbar fusion due to differences in spinal canal decompression methods,inter-body fusion approach,size and area of fusion cage used.
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