[Objective]To evaluate the value of bone scan in determining responsible vertebral fractures of percutaneous vertebroplas-ty in patients who were contraindicated to magnetic resonance imaging(MRI)in the diagnosis of multiple osteoporotic compression fractures(MOVCFs).[Methods]A retrospective study was performed on 14 patients who were treated for MOVCFs in our hospital from January 2013 to June 2022.All patients received X-ray,CT and bone scan examinations.The responsible vertebrae were determined based on bone scan and followed by percutaneous vertebroplasty(PVP)performed.The clinical outcome was evaluated.[Results]X-ray and CT showed a total of 32 vertebral compression fractures in 14 patients.However,bone scan showed that one of them had normal vertebral nuclide uptake,whereas the other 13 patients who had a total of 30 vertebral wedges change seen by X-ray and CT,had only 17 wedged vertebrae with up-take concentration on bone scan imaging,with a positive rate of 53.1％on bone scan imaging.As identified as responsible vertebrae,the 13 patients received PVP,including single segment in 9 cases and double segments in 4 cases.All patients had PVP performed successfully without complications.Compared with those preoperatively,VAS[(7.9±2.4),(3.6±1.8),(4.1±1.2),P＜0.001]and ODI[(42.4±6.8),(12.5± 3.1),(14.7±2.9),P＜0.001]scores decreased significantly 1 day postoperatively and at the latest follow up.[Conclusion]Bone scan is an ef-fective method to locate the responsible vertebrae in patients with multiple osteoporotic vertebral compression fractures if MRI is contraindi-cated.
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