首页|内镜下腰椎融合术失血的相关因素

内镜下腰椎融合术失血的相关因素

Factors associated with blood loss in endoscopic lumbar interbody fusion

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[目的]探讨内镜下腰椎融合术隐性失血量的相关因素.[方法]回顾性分析2018年9月-2022年6月行内镜下腰椎融合术的120例患者的临床资料,其中,经椎间孔入路内镜下腰椎融合术(endoscopic transforaminal lumbar interbody fusion,E-TLIF)37例,经椎板间内镜下腰椎融合术(endoscopic posterior lumbar interbody fusion,E-PLIF)30例,单侧双通道内镜下腰椎融合术(unilateral biportal posterior endoscopic lumbar interbody fusion,UBE-PLIF)53 例.采用单项因素比较,单因素相关分析和多元线性逐步回归分析隐性失血的相关因素.[结果]所有患者均顺利完成手术,三组间手术时间、术前Hb、RBC、Hct及凝血指标的差异均无统计学意义(P>0.05).术后三组Hb、RBC、Hct均较术前显著下降(P<0.05).E-TLIF组和E-PLIF组术后上述指标间差异无统计学意义(P>0.05).UBE-PLIF 组术后 1 d Hb[(111.7±12.7)g/Lvs(123.9±16.0)g/L,P<0.05]、RBC[(4.0±0.7)x 1012 vs(4.4±0.6)x1012,P<0.05]、Hct[(34.7±5.0)%vs(36.8±4.7)%,P<0.05]显著低于 E-TLIF 组.UBE-PLIF 的术中失血量[(161.8± 77.9)ml vs(63.8±45.1)ml vs(56.3±30.1)ml,P<0.05]、总失血量[(553.8±459.7)ml vs(257.2±283.1)ml vs(262.5±302.3)ml,P<0.05]、隐性失血量[(392.1±419.2)ml vs(193.4±269.9)ml vs(145.5±205.2)ml,P<0.05]均显著多于 E-TLIF 组和 E-PLIF 组,E-TLIF 组和 E-PLIF组间上述指标差异无统计学意义(P>0.05).单因素相关分析显示,手术方式和术前Hct与隐性失血量呈显著正相关(P<0.05).多元线性回归分析显示,UBE-PLIF手术方式、术前Het是隐性失血量的独立危险因素(P<0.05).[结论]内镜下腰椎融合术也存在大量隐性失血可能,其中UBE-PLIF手术隐性失血的风险更大.
[Objective]To investigate the factors related to hidden blood loss in endoscopic lumbar interbody fusion.[Methods]A retro-spective study was conducted in 120 patients who underwent endoscopic lumbar interbody fusion from September 2018 to June 2022.Of them,37 patients underwent endoscopic transforaminal lumbar interbody fusion(E-TLIF),30 patients underwent endoscopic posterior lum-bar interbody fusion(E-PLIF),and 53 patients were treated with unilateral biportal endoscopic posterior lumbar interbody fusion(UBE-PLIF).The univariate comparison,univariate correlation and multiple linear stepwise regression were conducted to research the factors relat-ed to the hidden blood loss.[Results]All patients had surgical procedures accordingly performed successfully with no significant differences in operation time,preoperative Hb,RBC,Hct and coagulation parameters among the three groups(P>0.05).The Hb,RBC and Hct of all the three groups significantly decreased after surgery(P<0.05),which were not significantly different between E-TLIF group and E-PLIF group(P>0.05),whereas the UBE-PLIF group was significantly lower than the E-TLIF group in terms of Hb[(111.7±12.7)g/L vs(123.9±16.0)g/L,P<0.05],RBC[(4.0±0.7)1012 vs(4.4±0.6)1012,P<0.05]and Het[(34.7±5.0)%vs(36.8±4.7)%,P<0.05].In addition,the UBE-PLIF group proved significantly greater than the E-TLIF and E-PLIF groups in terms of intraoperative blood loss[(161.8±77.9)ml vs(63.8±45.1)ml vs(56.3±30.1)ml,P<0.05],total blood loss[(553.8±459.7)ml vs(257.2±283.1)ml vs(262.5±302.3)ml,P<0.05]and hidden blood loss[(392.1± 419.2)ml vs(193.4±269.9)ml vs(145.5±205.2)ml,P<0.05],whereas there was no significant differences in the above indexes between the E-TLIF group and the E-PLIF group(P>0.05).As consequence of univariate correlation,the surgical method(UBE-PLIF)and preoperative Het were significantly positively correlated with hidden blood loss(P<0.05).Regarding to multiple linear regression analysis,the UBE-PLIF and preoperative Hct were independent risk factors for hidden blood loss(P<0.05).[Conclusion]Endoscopic lumbar interbody fusion also has the possibility of large amounts of hidden blood loss perioperatively,especially the UBE-PLIF.

lumbar interbody fusionsingle channel endoscopyunilateral bioportal endoscopyblood losshidden blood loss

葛志林、龙海光、钟家云、侯信合、江晓兵

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广州中医药大学,广东广州 510000

玉林市红十字会医院,广西玉林 537000

广州中医药大学第一附属医院,广东广州 510000

腰椎间融合术 单通道内镜 单侧双通道内镜 失血量 隐性失血

玉林市科学技术局科技计划项目

玉市科20220631

2024

中国矫形外科杂志
中国残疾人康复协会 中国人民解放军第八十八医院

中国矫形外科杂志

CSTPCD北大核心
影响因子:1.521
ISSN:1005-8478
年,卷(期):2024.32(4)
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