[Objective]To investigate the factors related to hidden blood loss in endoscopic lumbar interbody fusion.[Methods]A retro-spective study was conducted in 120 patients who underwent endoscopic lumbar interbody fusion from September 2018 to June 2022.Of them,37 patients underwent endoscopic transforaminal lumbar interbody fusion(E-TLIF),30 patients underwent endoscopic posterior lum-bar interbody fusion(E-PLIF),and 53 patients were treated with unilateral biportal endoscopic posterior lumbar interbody fusion(UBE-PLIF).The univariate comparison,univariate correlation and multiple linear stepwise regression were conducted to research the factors relat-ed to the hidden blood loss.[Results]All patients had surgical procedures accordingly performed successfully with no significant differences in operation time,preoperative Hb,RBC,Hct and coagulation parameters among the three groups(P>0.05).The Hb,RBC and Hct of all the three groups significantly decreased after surgery(P<0.05),which were not significantly different between E-TLIF group and E-PLIF group(P>0.05),whereas the UBE-PLIF group was significantly lower than the E-TLIF group in terms of Hb[(111.7±12.7)g/L vs(123.9±16.0)g/L,P<0.05],RBC[(4.0±0.7)1012 vs(4.4±0.6)1012,P<0.05]and Het[(34.7±5.0)%vs(36.8±4.7)%,P<0.05].In addition,the UBE-PLIF group proved significantly greater than the E-TLIF and E-PLIF groups in terms of intraoperative blood loss[(161.8±77.9)ml vs(63.8±45.1)ml vs(56.3±30.1)ml,P<0.05],total blood loss[(553.8±459.7)ml vs(257.2±283.1)ml vs(262.5±302.3)ml,P<0.05]and hidden blood loss[(392.1± 419.2)ml vs(193.4±269.9)ml vs(145.5±205.2)ml,P<0.05],whereas there was no significant differences in the above indexes between the E-TLIF group and the E-PLIF group(P>0.05).As consequence of univariate correlation,the surgical method(UBE-PLIF)and preoperative Het were significantly positively correlated with hidden blood loss(P<0.05).Regarding to multiple linear regression analysis,the UBE-PLIF and preoperative Hct were independent risk factors for hidden blood loss(P<0.05).[Conclusion]Endoscopic lumbar interbody fusion also has the possibility of large amounts of hidden blood loss perioperatively,especially the UBE-PLIF.
lumbar interbody fusionsingle channel endoscopyunilateral bioportal endoscopyblood losshidden blood loss