[Objective]To explore the clinical outcome of bone transport for severe traumatic tibial defect.[Methods]A retrospective study was done on 12 patients who received bone transport for severe traumatic tibial defect in our departments from May 2018 to July 2022.The perioperative and follow-up results were evaluated.[Results]All patients had the operation performed successfully without im-portant nerve and vascular injury during the operation.The length of bone defect was of(6.9±1.2)cm,the carrying time of external fixator was of(606.3±55.2)days,with the bone healing index of(62.4±5.0)day/cm.With time of 1 month after operation,frame removed and the latest follow-up lasted for(26.3±7.5)months,the HSS score[(71.4±7.5),(85.3±5.7),(90.2±3.2),P<0.001],AOFAS score[(70.4±4.9),(83.1± 4.4),(89.8±3.2),P<0.001],knee extension-flexion ROM[(98.8±5.2)°,(112.6±6.0)°,(123.6±4.3)°,P<0.001]and ankle dorsal extension-metatarsal flexion ROM[(44.1±2.6)°,(51.4±3.3)°,(58.8±2.8)°,P<0.001]increased significantly.The tibial length discrepancy between bi-lateral sides decreased significantly[(4.9±1.2)cm,(1.3±0.2)cm,(0.9±0.2)cm,P<0.001],the tibial alignment[excellent/good/fair/poor,(8/4/0/0),(12/0/0/0),(12/0/0/0),P=0.009]improved significantly over time.In addition,all patients got sound bony healing at both ends of the transported bone segment at the latest follow-up.[Conclusion]Bone transport is an effective method for the treatment of severe traumatic tibial defect.Designing the transport scheme in advance,especially the distal interface,is necessary to achieve smooth healing of the inter-face area.