[Objective]To compare the early results of general and local anesthesia for percutaneous kyphoplasty(PKP)in the treat-ment of thoracolumbar osteoporotic fractures.[Methods]A retrospective study was conducted on 104 patients who received PKP for thora-columbar osteoporotic fractures in our hospital from September 2022 to October 2023.According to preoperative doctor-patient communica-tion,51 patients had PKP performed under general anesthesia(GA),while other 53 patients were under local anesthesia(LA).The clinical and imaging data during hospitalization were compared between the two groups.[Results]The GA group proved significantly superior to the LA group in terms of operation time[(42.2±2.7 min)vs(53.6±4.1)min,P＜0.001],fluoroscopy times[(25.7±6.3)vs(32.4±9.6),P＜0.001]and Kolcaba comfort score[(83.4±8.6)vs(74.7±8.1),P＜0.001],whereas the former resumed walking significantly later than the latter[(29.5±5.5)hours vs(26.6±3.4)hours,P=0.002].There was no statistically significant difference in the incidence of early adverse reactions between the two groups(P＞0.05).Regarding imaging,the anterior vertebral height(AVH)and local kyphotic angle(LKA)were significantly improved postoperatively in both groups compared with those preoperatively(P＜0.05).At the discharge,the GA group was significantly su-perior to the LA group in terms of AVH[(23.5±1.3)mm vs(20.1±1.1)mm,P＜0.001]and LKA[(7.2±1.7)° vs(9.3±1.8)°,P＜0.001].[Conclu-sion]Compared with under local anesthesia,the PKP under general anesthesia does indeed reduce the operation time and radiation expo-sure,reconstruct the vertebral body better with considerably better comfort level.
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