[Objective]To investigate the clinical outcomes of surgical removal of gouty tophi in foot and ankle.[Methods]A retrospec-tive research was performed on 38 patients who underwent surgical removal of tophi in foot and ankle from December 2016 to June 2022.The clinical and laboratory data were evaluated.[Results]All patients had tophi in foot and ankle removed successfully with no complica-tions,and followed up from 6 to 12 months.Compared with those preoperatively,the VAS score[(6.3±1.1),(2.0±0.5),P＜0.001]and acute gout attack frequency[(3.5±0.9)times/month,(0.8～0.4)times/month,P＜0.001]significantly decreased,whereas the AOFAS score[(66.1±3.7),(79.1±3.6),P＜0.001],ankle dorsal flexion ROM[(8.8±2.8)°,(16.1±2.4)°,P＜0.001]and ankle plantar flexion ROM[(28.4±7.2)°,(41.6±4.5)°,P＜0.001]increased significantly at the latest follow up.In addition,compared with that preoperatively,the serum uric acid significant-ly declined at the latest follow up[(586.8±90)μmol/L,(392.1±21.5)μmol/L,P＜0.001].[Conclusion]Surgical removal of gouty tophi in foot and ankle does significantly reduce and control uric acid level,effectively relieve pain and improve ankle joint function,with good clinical ef-ficacy.
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