[Objective]To compare the clinical efficacy of percutaneous endoscopic lumbar interbody fusion with large channel(PE-LIF)versus open posterior lumbar interbody fusion(PLIF)for single-level and low-grade lumbar spondylolisthesis.[Methods]A retrospec-tive study was conducted on 56 patients who received lumbar fusion for the single-level and low-grade lumbar spondylolisthesis in our hos-pital from January 2020 to February 2023.According to preoperative dock-patient communication,27 patients underwent PELIF,while oth-er 29 patients received PLIF.The perioperative,follow-up and imaging data were compared between the two groups.[Results]The PELIF group proved significantly superior to the PLIF group in terms of total incision length[(8.3±1.5)cm vs(10.2±2.2)cm,P＜0.001],intraopera-tive blood loss[(151.9±99.5)ml vs(303.5±117.2)ml,P＜0.001],time to return walking[(2.2±0.9)days vs(3.3±0.9)days,P＜0.001],hospital-ization[5.9±1.8)days vs(8.6±2.3)days,P＜0.001],despite of the fact that the former was significantly inferior to the latter in terms of opera-tive time[(178.3±32.5)min vs(134.5±27.4)min,P＜0.001]and intraoperative fluoroscopy times[(34.3±7.1)times vs(12.0±4.0)times,P＜0.001].There was no significant difference in intraoperative complication rate and incision healing grade between the two groups(P＞0.05).As time went on during follow-up period lasted for(16.3±2.6)months,VAS score for leg pain,VAS score for back pain,ODI score and JOA score significantly improved in both groups(P＜0.05).The PELIF group had significantly lower lumbago VAS score than the PLIF group 3 days postoperatively[(2.6±1.9)vs(4.0±1.8),P=0.005],whereas there were no significant differences in the leg pain VAS score,ODI and JOA scores between the two groups at any time points accordingly(P＞0.05).As for imaging,the lumbar lordosis angle,intervertebral space height,slipping rate and spinal canal area significantly improved in both groups after surgery compared with those preoperatively(P＜0.05),while which were not statistically different between the two groups at any corresponding time points(P＞0.05).[Conclusion]Both PELIF and open PLIF can achieve satisfactory efficacy in the treatment of low-grade lumbar spondylolisthesis,but PELIF has the advantages of less trauma and quick recovery in early stage after operation over the PLIF.
NETL
NSTL
万方数据
