[Objective]To compare clinical efficacy of biportal endoscopic lumbar interbody fusion(BE-LIF)versus conventional hemi-lamiectomy lumbar interbody fusion(HL-LIF)for degenerative lumbar diseases.[Methods]A retrospective study was done on 78 patients who received surgical treatment for lumbar degenerative diseases in our hospital from March 2022 to November 2022.According to the re-sults of doctor-patient discussion,35 patients received BE-LIF,while other 41 patients underwent HL-LIF.The perioperative period,fol-low-up and auxiliary examination were compared between the two groups.[Results]Although the BE-LIF cohort consumed significantly lon-ger operative time than the HL-LIF cohort,the former proved significantly superior to the latter in terms of incision length[(7.1±1.0)cm vs(11.5±2.2)cm,P＜0.001],intraoperative blood loss[(240.0±121.2)ml vs(344.9±140.9)ml,P＜0.001],postoperative walking time[(3.2±0.5)days vs(4.4±0.5)days,P＜0.001].With time of the follow-up lasted for(15.8±2.3)months in a mean,the VAS,ODI and JOA scores in both groups significantly improved(P＜0.05).The BE-LIF group was significantly better than the HL-LIF group in terms of low back pain VAS[(1.4±0.5)vs(1.8±0.7),P=0.005],ODI[(15.3±2.5)vs(16.7±3.2),P=0.039]and JOA score[(25.3±1.0)vs(24.2±1.5),P＜0.001]5 months af-ter surgery.As for imaging,the intervertebral space height and the lumbar lordosis were significantly increased in both groups after surgery(P＜0.05).However,there were no significant differences in intervertebral space height,lumbar lordosis and intervertebral fusion Bridwell grade between the two groups at any time points accordingly(P＞0.05).[Conclusion]Both of the lumbar fusion methods achieved good clini-cal outcomes.By comparison,the BE-LIF takes advantage of minimally invasive surgery,with less pain in early stage after operation and faster function recovery over the HL-LIF.
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