[Objective]To investigate the short-term efficacy of three-dimensional balanced chiropractic manipulation in the treatment of ankylosing spondylitis(AS).[Methods]A total of 102 patients visited our hospital from January 2021 to June 2023 for AS were selected,and divided into two cohorts with 51 cases in each cohor by random number table method.Of them,the patients who received routine western medicine combined with three-dimensional balanced chiropractic manipulation were termed as CM group,while those who received routine western medicine only were named as RT group.The clinical,laboratory test and imaging data of the two groups were compared.[Results]Compared with those before treatment,VAS for pain,Bath ankylosing spondylitis disease activity index(BASDAI),Bath ankylosing spondyli-tis functional index(BASFI),finger-ground distance and occipit-wall distance significantly decreased(P＜0.05),while thoracic cage motion and Schober test significantly increased in both groups 3 months after treatment(P＜0.05).The CM cohort proved significantly superior to the RT cohort in terms of pain VAS[(2.6±0.8)vs(3.8±1.0),P＜0.001],BASDAI[(1.7±0.5)vs(2.8±0.6),P＜0.001],BASFI[(14.8±5.5)vs(35.4±8.6),P＜0.001]and finger-ground distance[(15.4±5.0)cm vs(19.3±6.2)cm,P＜0.001],occipit-wall distance[(1.7±0.5)cm vs(2.5±0.6)cm,P＜0.001],thoracic cage mobility[(3.6±0.9)cm vs(2.9±0.7)cm,P＜0.001]and Schober test[(4.9±1.0)cm vs(3.4±0.8)cm,P＜0.001]3 months after treatment.In addition,the CM group also was significantly better than the RT group in terms of ESR,CRP,IL-6,IL-17 and IL-23 as-sayed in blood tests 3 months after treatment(P＜0.05).Furthermore,the CM was significantly better than the RT group regarding sagittal ver-tical axis(SVA),thoracic kyphosis(TK),lumbar lordosis(LL),pelvic incidence(PI),pelvic tilt(PT)and sacral slope(SS)measured on images 3 months after treatment(P＜0.05).[Conclusion]The three-dimensional balanced chiropractic manipulation is safe and effective in the treat-ment of AS,which can significantly relieve pain,improve spinal function and blood test and imaging parameters.
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