[Objective]To investigate the relationship between the ultrasonic morphology of the medial stable structures of knee osteoar-thritis(KOA)and the clinical presentations of the knee.[Methods]A total of 202 patients with unilateral knee KOA hospitalized in our hos-pital from March 2023 to March 2024 were included in this study.The ultrasound measurements and clinical data of the patients were col-lected.The correlation between ultrasonic measurements and the clinical presentations of KOA was analyzed.[Results]According to the self-reported knee instability score,the patients were divided into two groups.Of them,140 patients were fall into the unstable group,ac-counting for 69.3％;while other 62 patients(30.7％)were in the stable group.The unstable group proved significantly greater than the stable group regarding to WOMAC[(45.2±4.8)vs(29.8±3.8),P＜0.001],VAS[(6.3±1.7)vs(4.4±1.5),P＜0.001],JLCA[(5.4±1.3)° vs(2.9±1.1)°,P＜0.001],the thickness of the medial collateral ligament[(3.5±1.4)mm vs(2.9±1.3)mm,P＜0.001],extrusion of medial meniscus[(3.8±1.4)mm vs(2.2±0.9)mm,P＜0.001],whereas the former was significantly less than the latter in terms of HSS score[(65.3±5.1)vs(88.6±3.2),P＜0.001],knee flexion-extension ROM[(118.4±5.3)° vs(130.5±5.13)°,P＜0.001],HKA angle[(170.9±3.7)° vs(176.2±3.1)°,P＜0.001],the muscle thickness[(1.8±0.6)cm vs(2.4±0.5)cm,P＜0.001]and the cross-sectional area of the medial vastus muscle[(9.1±2.2)cm2 vs(11.3±2.4)cm2,P＜0.001].There was no significant difference in K-L rating between the two groups(P＞0.05).Paired correlation analysis showed that the thickness and cross-sectional area of the vastus medialis muscle were significantly positively correlated with self-reported knee in-stability score,HSS score,HKA angle and knee flexion-extension ROM(P＜0.05),while significantly negatively correlated with WOMAC,VAS and JLCA angle(P＜0.05).On the contrary,medial collateral ligament thickness and medial meniscus extusion were significantly nega-tively correlated with self-reported knee instability score,HSS score,HKA angle and knee ROM score(P＜0.05),but were significantly posi-tively correlated with WOMAC,VAS and JLCA angle(P＜0.05).There was no correlation between the above ultrasound indicators and K-L rating.As results of multiple linear stepwise regression,the cross-sectional area of vastus medialis muscle(B=-0.101,P＜0.05),thickness of medial collateral ligament(B=0.112,P＜0.05)and medial meniscus extrusion(B=0.132,P＜0.05)were the factors affecting knee joint func-tion.[Conclusion]For patients with self-reported knee instability,ultrasound detection of medial knee structure has clinical guiding signifi-cance.
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