首页|内侧室骨关节炎单髁与全膝置换倾向评分匹配比较

内侧室骨关节炎单髁与全膝置换倾向评分匹配比较

A propensity-score matching comparison of unicompartmental knee arthroplasty and total knee arthroplasty for medial compartment osteoarthritis of the knee

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[目的]比较单髁置换术(unicomparmental knee arthroplasty,UKA)和全膝置换(total knee arthroplasty,TKA)治疗膝内侧间室骨性关节炎的近期临床结果.[方法]回顾性分析2021年1月—2023年8月本院关节置换治疗457例膝内侧室骨性关节炎变患者的临床资料,采用PSM匹配,最终纳入本研究的UKA和TKA患者各为88例,比较两组围手术期、随访及影像资料.[结果]UKA 组手术时间[(74.6±8.1)min vs(85.4±8.7)min,P<0.001]、切 口长度[(7.1±0.9)cm vs(14.4±2.6)cm,P<0.001]、术中失血量[(174.6±33.5)ml vs(305.7±68.9)ml,P<0.001]、术后引流量[(22.7±3.6)ml vs(43.5±6.7)ml,P<0.001]、下地行走时间[(2.7±0.5)h vs(4.7±1.1)h,P<0.001]、切口愈合等级[甲/乙/丙,(32/48/8)vs(21/48/19),P=0.034]、住院时间[(8.1±1.9)d vs(11.1±2.7)d,P<0.001]和治疗费用[(4.7±1.1)万元vs(5.1±1.4)万元,P=0.012]均显著优于TKA组.UKA组患者恢复完全负重活动显著早于TKA组(P<0.05).随时间推移,两组患者VAS、HSS、WOMAC评分和ROM均显著改善(P<0.05).术后1个月和末次随访时,UKA组的VAS、HSS、WOMAC评分和ROM均显著优于TKA组(P<0.05).但是,两组间远期并发症发生率的差异无统计学意义(P>0.05).辅助检查方面,术后1个月时,UKA组滑液TNF-α、TGF-β1水平均显著优于TKA组(P<0.05).末次随访时,UKA组的FTA、MPTA、PTS及MAD均优于TKA组(P<0.05).[结论]对膝内侧间室骨性关节炎,UKA的手术创伤更小,近期临床结果优于TKA.
[Objective]To compare the short-term clinical outcomes of unicompartmental knee arthroplasty(UKA)versus total knee ar-throplasty(TKA)for medial compartment osteoarthritis of the knee.[Methods]A retrospective analysis was performed on 457 patients who received arthroplasty for medial compartment osteoarthritis of the knee in our hospital from January 2021 to August 2023.By propensity-score matching(PSM)method,88 patients underwent UKA and 88 received TKA were finally included in this study.The document regard-ing perioperative period,follow-up and auxiliary examinations were compared between the two groups.[Results]The UKA group proved sig-nificantly superior to the TKA group in terms of operation time[(74.6±8.1)min vs(85.4±8.7)min,P<0.001],incision length[(7.1±0.9)cm vs(14.4+2.6)cm,P<0.001],intraoperative blood loss[(174.6±33.5)ml vs(305.7±68.9)ml,P<0.00l],postoperative drainage[(22.7±3.6)ml vs(43.5±6.7)ml,P<0.001],ambulation time[(2.7±0.5)hours vs(4.7±1.1)hours,P<0.001],as well as incision healing grade,hospital stay and treatment cost.In addition,the patients in UKA group resumed full weight-bearing activities significantly earlier than those in TKA group(P<0.05).The VAS,HSS,WOMAC scores and ROM significantly improved in both groups over time(P<0.05).The UKA was signifi-cantly better than the TKA group regarding to VAS,HSS,WOMAC score and ROM 1 month postoperatively and at the last follow-up(P<0.05).However,there was no significant difference in the incidence of later complications between the two groups(P>0.05).As for auxiliary examination,the UKA group was also significantly better than the TKA group in terms of the levels of TNF-α and TGF-β1 in synovial fluid 1 month after surgery(P<0.05).At the last follow-up,the UKA group got significantly better femorotibial angle(FTA),medial proximal tibial angle(MPTA),posterior tibial slope(PTS)and mechanical axis deviation(MAD)on images than the TKA group(P<0.05).[Conclusion]For medial compartment osteoarthritis of the knee,UKA is less invasive and has better short-term clinical outcomes than TKA.

knee osteoarthritissingle-compartment involvementunicompartmental knee arthroplastytotal knee arthroplasty

叶楠、刘晓龙、何爱民、杨强、王晓阳、黄健

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内蒙古医科大学第二附属医院关节外科,内蒙古呼和浩特 010010

膝骨性关节炎 单间室病变 单髁置换术 全膝关节置换术

内蒙古自治区高等学校"青年科技英才发展项目"内蒙古自治区自然科学基金(面上项目)

NJYT240452021MS08095

2024

中国矫形外科杂志
中国残疾人康复协会 中国人民解放军第八十八医院

中国矫形外科杂志

CSTPCD北大核心
影响因子:1.521
ISSN:1005-8478
年,卷(期):2024.32(17)