[Objective]To investigate the clinical efficacy of 3D printed guide assisted calcaneal osteotomy in the treatment of Haglund syndrome.[Methods]A retrospective study was done on 37 patients who received surgical treatment for Haglund syndrome in our hospital from January 2021 to June 2022.According to of doctor-patient communication preoperatively,17 patients had osteotomy performed with the 3D printed guide(the guide group),while other 20 patients was with conventional free hand technique(the free-hand group).Clinical and imaging documents were compared between the two groups.[Results]The guide group proved significantly less than the free-hand group in terms of operation time[(42.8±4.1)min vs(50.2±4.2)min,P<0.001]and intraoperative fluoroscopy times[(0.6±0.6)times vs(2.2±0.9)times,P<0.001],but there was no significant difference in incision length and intraoperative blood loss between the two groups(P>0.05).All patients were followed up for a mean of(18.3±7.5)months.Compared with those preoperatively,the VAS score and AOFAS score in both groups were significantly improved at the last follow-up(P<0.05).At the last follow-up,the guide group was significantly better than the free-hand group regarding AOFAS score[(96.5±2.9)vs(94.4±3.3),P=0.047].As for imaging,the posterior calcaneal angle(Fowler-Philipp angle,FPA)and X/Y ratio in both groups significantly improved at the last follow-up compared with those preoperatively(P<0.05).Although the FPA and X/Y ratio were not significantly different between the two groups before surgery(P>0.05),the guide group got signifi-cantly greater FPA than the free-hand group at the latest follow up[(65.6±1.9)° vs(61.8±4.9)°,P<0.005].[Conclusion]Compared with tra-ditional free-hands calcaneal osteotomy,3D printied guide assisted calcaneal osteotomy has better therapeutic effect in the treatment of Ha-glund syndrome,improving surgical accuracy and reducing surgical injury.