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双层人工真皮修复指端缺损并骨外露

Double-layer artificial dermis for repair of finger tip defect complicated with bone exposed

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[目的]探讨Lando®双层人工真皮修复材料修复指端缺损伴指骨外露创面的临床疗效.[方法]2020年1月—2022年12月作者对30例(30指)因各种外伤导致手部指端缺损合并指骨外露患者行清创后,采用双层人工真皮缝合于缺损处,打包加压包扎.术后7~10d拆除加压缝合包,术后3周拆除缝线,术后4周揭除双层人工真皮表面硅胶膜,让创面自然上皮化.观察创面愈合外观及功能恢复,评估疗效.[结果]30例患者中,27例创面均一期愈合;2例患者部分创面残留,但无骨外露,换药后愈合;1例患者术后仍部分肌腱外露,再次行双层人工真皮移植修复后愈合.所有创面自然上皮化时间平均为(60.1±8.8)d.术后随访均超过6个月,创面愈后指腹饱满,色泽良好,皮肤感觉良好.与术后3个月相比,术后6个月两点辨别觉显著改善[(3.8±1.1)mm,(2.5±0.9)mm,P<0.001].[结论]双层人工真皮一期修复指端合并骨外露缺损创面操作简单,供区损伤小,疗效可靠.
[Objective]To investigate the clinical efficacy of Lando® double-layer artificial dermis used for repair of finger tip defect complicated with bone exposed.[Methods]From January 2020 to December 2022,30 patients(30 fingers)had double-layer artificial der-mis with pressure dressing used after debridement to repair the finger tip defect complicated with bone exposed.The compression suture kit was removed 7~10 days after surgery,the sutures were removed 3 weeks after surgery,while the surface silicone film over double layer arti-ficial dermis was removed 4 weeks after surgery to allow the wound to be naturally epithelialized.The appearance of wound healing and functional recovery were observed,and the curative effect was evaluated.[Results]Of the 30 patients,27 patients got wound healing in one stage,2 patients had a part of the wound remained without bone exposure,and got wound healed after dressing change,whereas one patient remained a part of the tendon exposure after surgery,and had the tendon healed after revision double-layer artificial dermis implantation.All the patients were followed up for more than 6 months,with the mean time of natural epithelialization of(60.1±8.8)days.After the wound healed,the finger belly was well-stacked with good color and proper skin sensation.Compared with that 3 months after surgery,the average two-point discrimination was significantly improved at 6 months after surgery[(3.8±1.1)mm,(2.5±0.9)mm,P<0.001].[Conclusion]This double-layer artificial dermis used to repair of finger tip defect with bone exposed in one stage is simple and effective technique without do-nor area damage.

artificial dermisfinger tip defectbones exposurenatural epithelialization

王琳、边洪琳、赵大龙、何旭、陈君

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康复大学青岛中心医院(青岛市中心医院)手足创伤外科,山东青岛 266000

人工真皮 指端缺损 骨外露 自然上皮化

2024

中国矫形外科杂志
中国残疾人康复协会 中国人民解放军第八十八医院

中国矫形外科杂志

CSTPCD北大核心
影响因子:1.521
ISSN:1005-8478
年,卷(期):2024.32(18)
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