[Objective]To compare the short-term clinical outcomes of fixed-bearing unicompartmental knee arthroplasty(FB-UKA)verus mobile bearing unicompartmental knee arthroplasty(MB-UKA)for medial knee osteoarthritis.[Methods]A retrospective study was conducted on 98 patients who received UKA for medial knee osteoarthritis from January 2020 to February 2023.According to the results of doctor-patient communication,43 underwent FB-UKA with Zimmer prosthesis,while other 55 patients were treated with MB-UKA by using Oxford prosthesis.The data of perioperative period,follow-up and images were compared between the two groups.[Results]All patients in both groups had UKA performed successfully without statistically significant differences in operation time,incision length,intraoperative blood loss,ambulation time,incision healing grade,hospital stay and hospital cost between the two groups(P>0.05).All of them in both groups were followed up for(12.7±4.8)months in an average,and there was no significant difference in the time to regain full weight-bearing activities between the two groups(P>0.05).The VAS and WOMAC scores significantly decreased(P<0.05),while HSS score,forgotten joint score(FJS)and knee extension-flexion ROM significantly increased in both groups at the latest follow-up compared with those preoperative-ly(P<0.05).At the last follow-up,the MB group was significantly better than the FB group in terms of FJS[(85.5±3.5)vs(84.1±2.7),P=0.032],and knee extension-flexion ROM[(125.4±3.5)° vs(123.7±4.2)°,P=0.031].As for imaging,HKAA and JICA were significantly im-proved in both groups after surgery(P<0.05),while TPVA remained unchanged significantly(P>0.05).At corresponding time points,there were no significant differences in the above imaging items between the two groups(P>0.05).[Conclusion]For medial knee osteoarthritis,the MB-UKA has better forgotten joint score regarding to short-term clinical consequence over the FB-UKA.