[Objective]To compare clinical outcomes of percutaneous Kambin's triangle approach lumbar interbody fusion(PKLIF)versus minimal invasive transforaminal lumbar interbody fusion(MIS-TLIF)for degenerative lumbar spondylolisthesis(DLS).[Methods]A retrospective study was conducted on 32 patients who had DLS treated surgically in our hospital from March 2023 to March 2024.Accord-ing to preoperative doctor-patient communication,15 patients received PKLIF with self-developed instruments,while other 17 patients re-ceived routine MIS-TLIF.Clinical and imaging data of the two groups were compared.[Results]All patients had the corresponding surgical procedures performed successfully without serious complications such as nerve injury and death,and were followed up in a mean of(6.0±1.8)months.The PKLIF group proved significantly superior to the MIS-TLIF group in terms of intraoperative blood loss[(82.7±9.6)ml vs(165.3±25.3)ml,P＜0.001],postoperative ambulation time[(1.9±0.7)days vs(3.1±0.6)days,P＜0.001],hospital stay[(8.3±2.2)days vs(11.7±2.6)days,P＜0.001],back pain VAS score one day postoperatively[(1.8±0.7)vs(2.9±0.7),P＜0.001]and ODI score 2 weeks after op-eration[(31.2±3.0)vs(40.6±5.8),P＜0.001].However,the PKLIF group was significantly greater than the MIS-TLIF group regarding intra-operative fluoroscopy times[(17.7±1.7)times vs(5.1±1.0)times,P＜0.001]and operation time[(134.0±12.4)min vs(115.9±13.7)min,P＜0.001].[Conclusion]PKLIF does relieve clinical symptoms of DLS,with the advantages of less intraoperative blood loss,early ambulation,and shortened hospitalization,whereas disadvantages of more intraoperative fluoroscopy times and longer operation time compared with the MIS-TLIF.
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