The application of flipped classroom teaching method in the teaching of Oral Anatomy and Physiology is investigated,with the construction of"flipped classroom"teaching method as the focal point,in order to adapt to the requirements of educational development under the background of big data.The model of flipped classroom teaching method is constructed,and good learning results are achieved,with the goal of improving students'innovative ability and independent learning ability,and the application advantages of flipped classroom teaching method in teaching as the core.Based on this,this paper first analyzes the significance of introducing the flipped classroom teaching mode into the teaching of Oral Anatomy and Physiology,then compares the differences between the traditional teaching mode and the flipped classroom teaching mode through teaching experiments,and then points out the advantages of applying the flipped classroom teaching mode in the teaching of Oral Anatomy and Physiology.Finally,the paper puts forward the way of applying the flipped classroom teaching mode in the teaching of Oral Anatomy and Physiology,aiming at providing reference for the teaching reform of Oral Anatomy and Physiology.