基于MRI的骨质疏松椎体压缩骨折患者椎旁肌特征定量分析研究
MRI-based quantitative analysis of paraspinal muscle characteristics in patients with osteoporotic ver-tebral compression fractures
陈泽正 1王方永 2张文捷 1尹浩然1
作者信息
- 1. 首都医科大学康复医学院 100069 北京市;中国康复研究中心北京博爱医院脊柱脊髓外科 100069 北京市
- 2. 首都医科大学康复医学院 100069 北京市;中国康复研究中心北京博爱医院脊柱脊髓外科 100069 北京市;康复大学 266555 青岛市
- 折叠
摘要
目的:对比分析骨质疏松性椎体压缩性骨折(osteoporotic vertebral compression fracture,OVCF)患者和非OVCF患者腰椎MRI特征,脂肪浸润率(fatty infiltration,FI),探讨其与骨折发生的关系.方法:回顾性分析46例OVCF患者(70.67±11.99岁;男11例,女35例)的临床资料,以46例年龄(70.76±5.40岁)、性别(男11例,女35例)匹配的不伴OVCF的患者作为对照组.在腰椎MRI上测量椎旁肌FI、肌肉横截面积(cross-sectional area,CSA)和椎体骨质量(vertebral bone quality,VBQ)评分.采用独立样本t检验比较OVCF组与对照组之间的差异,并进行回归分析,探索OVCF发生的风险因素.结果:OVCF组患者的VBQ评分显著高于对照组(P＜0.05),椎旁肌FI显著高于对照组(P＜0.05).两组椎旁肌CSA无显著差异.VBQ评分(OR=1.963,P＜0.01)和LA代表的椎旁肌FI(OR=1.203,P＜0.01)是 OVCF的独立风险因素.结论:OVCF患者的腰椎MRI参数与非OVCF的骨质疏松患者相比,VBQ评分及椎旁肌FI均较大,VBQ评分、椎旁肌FI是OVCF的独立风险因素,预防OVCF同时应重视对椎旁肌功能的改善.
Abstract
Objectives:To compare and analyze the MRI characteristics and fatty infiltration(FI)of the lum-bar spine in patients with and without osteoporotic vertebral compression fracture(OVCF)to explore their rela-tionships with fracture.Methods:46 patients with OVCF(70.67±11.99 years old;11 males,35 famales)were retrospectively analyzed,and 46 age-(70.76±5.40)and sex-(11 males,35 famales)matched osteoporotic pa-tients without OVCF were taken as the control group.Paravertebral muscle FI,cross-sectional area(CSA),and vertebral bone quality(VBQ)score were measured on lumbar MRI.Independent samples t-test was used to compare the differences between the OVCF group and the control group,and regression analysis was per-formed to explore the risk factors for the development of OVCF.Results:Patients in the OVCF group had significantly higher VBQ scores(P＜0.05)and significantly higher paravertebral muscle FI(P＜0.05)than those in the control group.There was no significant difference in CSA of paravertebral muscles between the two groups.VBQ score(OR=1.963,P＜0.01)and FI of paravertebral muscles represented by L4(OR=1.203,P＜0.01)were the independent risk factors for OVCF.Conclusions:The MRI parameters of lumbar spine in patients with OVCF had greater VBQ scores and paravertebral muscle FI compared with the osteoporotic patients without OVCF;VBQ scores and paravertebral muscle FI are the independent risk factors for OVCF,and at-tentions should be paid to improve paravertebral muscle functions in the meantime of preventing OVCF.
关键词
骨质疏松性椎体压缩骨折/脊柱椎旁肌肉/脂肪浸润率/椎体骨质量评分/磁共振成像Key words
Osteoporotic vertebral compression fractures/Paraspinal muscle/Fatty infiltration/Vertebral bone quality score/Magnetic resonance imagine引用本文复制引用
基金项目
首都卫生科研发展专项(CFH2022-2-6013)
出版年
2024
NETL
NSTL
万方数据