目的 基于静息脑电(EEG)分析认知障碍老年人身体活动、睡眠质量与认知功能的关系,探讨特异性EEG指标在身体活动影响睡眠质量中的中介作用.方法 2024年3月至5月,于上海市松江区辰富佳苑、蔷薇九里社区和金山区鲁堰社区招募137例认知障碍老年人,使用蒙特利尔认知评估量表(MoCA)、国际身体活动问卷短卷(IPAQ-SF)和匹兹堡睡眠质量指数(PSQI)进行评估,并采集5 min EEG信号.结果 不同认知障碍程度老年人的PSQI评分有非常高度显著性差异(t=-7.400,P<0.001).PSQI总分与MoCA评分呈显著负相关(r=-0.412,P<0.001),与身体活动水平(PAL)呈显著负相关(r=-0.363,P<0.001).θ(F3、F4)功率值与PSQI总分和PAL均呈显著相关(P<0.01).身体活动可通过θ(F3+F4)功率值的部分中介(效应量-0.0004,95%CI-0.0007～-0.0002)路径对认知障碍老年人的睡眠质量产生影响.结论 老年人的认知障碍越严重,睡眠质量越差;身体活动水平越高,睡眠质量越好.身体活动可通过影响θ(F3+F4)功率值间接影响认知障碍老年人的睡眠质量.
Relationship of physical activity and cognitive function to sleep quality in older adults with cognitive impairment:a mediating effect of resting EEG
Objective To investigate the relationship of physical activity(PA)and cognitive function to sleep quality in older adults with cognitive impairment based on resting electroencephalogram(EEG),and to explore the mediating role of specific EEG markers in the relationship between PA and sleep quality.Methods From March to May,2024,137 older adults were recruited from Chenfu Jiayuan and Qiangwei Jiuli in Songji-ang district,and Luyan communities in Jinshan district,Shanghai.The assessments included Montreal Cognitive Assessment(MoCA),International Physical Activity Questionnaire-Short Form(IPAQ-SF)and Pittsburgh Sleep Quality Index(PSQI),along with a five-minute EEG recording.Results There was significant difference in sleep quality among older adults with different levels of cognitive impair-ment(t=-7.400,P<0.001).The PSQI total score was negatively correlated with MoCA scores(r=-0.412,P<0.001)and total physical activity level(PAL)(r=-0.363,P<0.001).The θ power in the frontal areas(F3,F4)was significantly correlated with both PSQI scores and PAL(P<0.01).The θ power in F3+F4 exhibited a sig-nificant partial(effect size=-0.0004,95%CI-0.0007 to-0.0002)mediating effect between PA and sleep quali-ty in older adults with cognitive impairment.Conclusion Older adults with more severe cognitive impairment tend to have poorer sleep quality,whereas higher PAL is associated with better sleep quality.PA can indirectly influence sleep quality in older adults with cognitive im-pairment by affecting θ power(F3+F4).
万方数据
维普
