Association of different grades of sarcopenia and 10-year atherosclerotic cardiovascular disease risk
Objective:To analyze the correlation between different grades of sarcopenia and 10-year atherosclerotic cardio-vascular disease risk,and provide the scientific evidence for prevention of sarcopenia and cardiovascular disease.Method:The study included 1,072 elderly individuals who completed physical examination program for seniors 65 years and older at Beijing Zhongguancun Hospital from January 2021 to June 2022,consisting of 408 men and 664 women.The investigation was performed with the questionnaires,physical examination,biochemical,body composition and physical performance test.According to handgrip strength,5-time chair stand test and ASMI,the subjects were divided into control,possible sarcopenia,pre-sarcopenia and sarcopenia group.Bina-ry logistic regression method was used to analyze the data.Result:The prevalence of disease for sarcopenia was 10.6％,with the detection rates of possible sarcopenia and pre-sarcopenia being 16.1％and 15.1％,respectively.In male,pre-sarcopenia[OR:95％Cl=3.63(1.03-12.78),P=0.04]and sarcopenia[OR:95％C1=8.90(1.15-68.86),P=0.04]were correlated with a high 10-year risk of atherosclerotic cardiovascular disease.In female,sarcopenia[OR:95％Cl=5.05(1.49-17.13),P=0.009]was significantly correlated with a high 10-year risk of atherosclerotic cardiovascular disease.Conclusion:Both male and female elderly sarcopenia patients,as well as males with reduced muscle mass,have a higher 10-year risk of developing ASCVD.The severity of sarcopenia is positively correlated with the risk of ASCVD,underscoring the importance of early prevention of cardiovascular disease.
sarcopenia10-year atherosclerotic cardiovascular diseasemorbidity riskmuscle mass
万方数据
维普
