摘要
目的:应用功能性近红外光谱技术(functional near-infrared spectroscopy,fNIRS)观察健康成年人在进行感觉统合测试(sensory organization test,SOT)伴或不伴听觉认知任务时的平衡表现及背外侧前额叶(dorsolateral prefrontal cortex,DLPFC)激活差异.方法:招募健康受试者11例,分别进行单双任务测试.单任务测试时仅进行SOT,双任务测试为SOT+听觉Stroop测试;测试同时,运用fNIRS测量大脑的血氧浓度,分析单、双任务下前额皮层氧合血红蛋白(oxyhemoglobin,HbO2)浓度变化的差异,以对比激活情况.同时观察的平衡测试指标为SOT得分.结果:受试者在单、双任务平衡测试中SOT得分无显著差异(P=0.152).对比休息状态,受试者执行6种SOT双任务及单任务SOT6时,DLPFC区域平均HbO2浓度变化量有显著升高;当对比双任务与单任务的差异时,SOT1、SOT2、SOT3和SOT5的双任务DLPFC区的HbO2浓度变化对比单任务时具有显著性增高(P＜0.05),SOT4和SOT6则无显著差异.结论:健康成年人在进行SOT时同时进行听觉认知测试,其平衡表现虽与单独进行SOT无差异,但通过fNIRS技术可以观察到DLPFC区域脑激活差异.单、双任务对比下,DLPFC区域脑激活的显著差异说明在双任务环境下维持姿势的稳定需要更多的认知资源;同时也说明DLPFC在姿势—认知双任务中的重要作用.
Abstract
Objective:To observe the changes of blood oxygen concentration in dorsolateral prefrontal cortex(DLPFC)by functional near-infrared spectroscopy(fNIRS)as well as the postural performance under dual cognitive-balance task versus single balance task in healthy adults.Method:Eleven healthy adults were asked to keep stability during sensory organization test(SOT)only or with a modified auditory Stroop task.fNIRS was used to measure the cerebral blood oxygen concentration of the prefrontal cortex concurrently.The changes of HbO2 were compared between single and dual task,and the pos-tural performance measured by total score of SOT was compared also.Result:There was significant increase of HbO2 concentration in all dual task conditions and in SOT6(single task)compared with resting period;the increasement indicated by the HbO2 concentration were significant(P＜0.05)in SOT1,SOT2,SOT3,SOT5 but not in SOT4 and SOT6.The postural performance showed no differ-ence under single versus dual task(P=0.152).Conclusion:Although postural performances under dual and single condition showed no difference,the signifi-cant activation of the DLPFC measured by fNIRS were showed in dual task versus single task in healthy adults.The difference of DLPFC activation between single and dual tasks indicates that the DLPFC region plays an important role in the dual tasks and dual-tasking is cognitive consuming.
维普
万方数据