Jaw defect is one of the most common diseases in oral and maxillofacial surgery.Severe jaw defect will cause different degrees of impact on the life and psychology of patients,and needs timely and effective repair.Due to the u-nique physiologic appearance and individual differences of jaw bones,the repair of jaw defects can't be completely depen-dent on standardized bone prosthetics.With the development and maturity of related manufacturing technologies,especial-ly the unique advantages of 3D printing technology in bone defect repair,it has attracted wide attention of scholars both at home and abroad.The repair of bone defects is a complex and precise process.The ideal biomaterials for repairing bone defects should have good histocompatibility,suitable mechanical stress,suitable pore size,and solubility.This article briefly reviewed the existing high-active bone replacement materials for jaw tissue engineering.