Chondromyxoid fibroma(CMF)is an exceedingly rare benign bone tumor,to the authors'knowledge,only one case primarily occurred in temporomandibular joint(TMJ)has been reported in the literature.This paper presented a pa-tient with TMJ-CMF involving pterygopalatine space,and the skull base thereof.Digital technique was used to determine the boundary of the lesion and reconstruct the normal glenoid fossa,the temporalis myofascial flap was transplanted be-tween titanium mesh and condyle so as to reconstruct the disk after complete resection of the tumor.The patient's facial profile is symmetrical,with a mouth opening of 45 mm.There was no local recurrence,no complications such as cere-brospinal fluid fistula and cerebral hernia during 1-year follow-up period.