首页|芽胞杆菌抑菌物质作用研究进展

芽胞杆菌抑菌物质作用研究进展

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芽胞杆菌是土壤和植物微生态的优势微生物种群,具有很强的抗逆能力和抗菌防病作用,是目前研究和应用较多的一类生防菌.芽胞杆菌可产生醇、酮和酸等多种挥发性物质,能够有效抑制多种病原菌的生长.此外,芽胞杆菌还能合成多种非挥发性抑菌物质如脂肽类化合物、聚酮类化合物和环二肽等抑制某些细菌和真菌的生长.芽胞杆菌的有效抑菌物质主要通过破坏病原菌的细胞壁、细胞膜及影响病原菌的代谢通路发挥其抑菌活性.本文主要总结了芽胞杆菌发酵液中的挥发性、非挥发性抑菌物质及其抑菌机制,为芽胞杆菌作为生防菌的深度开发与应用提供参考.
Research advances on the antimicrobial effect of bacteriostatic substances from Bacillus spp.
Bacillus spp.are the dominant microbial population in soil and plant microecology.Bacillus is a type of biocontrol bacteria that has been extensively studied and applied due to its anti-adversity ability and good antimicrobial activity.Bacillus spp.can produce a variety of volatile substances,such as alcohols,ketones and acids,which can effectively inhibit the growth of many microbial pathogens.In addition,Bacillus spp.can also synthesize a variety of non-volatile inhibition substances,such as lipopeptides,polyketides and cyclic dipeptides,to inhibit the growth of certain bacteria and fungi.The antimicrobial mechanisms of Bacillus spp.mainly involve the disruption of the cell walls and membranes of pathogenic bacteria and the interference of the metabolic pathways of pathogenic bacteria and fungi.This article summarized the volatile and non-volatile inhibition substances from Bacillus spp.fermentation broth and their inhibition mechanisms,and provided a reference for the in-depth development and application of Bacillus spp.as biocontrol bacteria.

Bacillus spp.Secondary metabolitesAntimicrobial mechanism

白穆冉、于婷、陈培、李晓岩

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东北林业大学生命科学学院,哈尔滨 150040

芽胞杆菌 次生代谢产物 抑菌机制

2024

中国抗生素杂志
中国医药集团总公司四川抗菌素工业研究所,中国医学科学院医药生物技术研究所

中国抗生素杂志

CSTPCD北大核心
影响因子:1.08
ISSN:1001-8689
年,卷(期):2024.49(5)
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