New oxazolidinone drugs and perspectives for anti-tuberculosis agents
The global situation of drug-resistant tuberculosis is severe,with limited drug options available for the treatment of drug-resistant tuberculosis,resulting in challenges and difficulties in treatment.The development of new anti-tuberculosis drugs plays a crucial role in the treatment of drug-resistant tuberculosis.Oxazolidinone drugs and their structural derivatives have shown good antibacterial activity against drug-resistant strains of Mycobacterium tuberculosis.This article reviewed recent advances in the understanding of the mechanism of action,preclinical studies on the anti-tuberculosis activity,pharmacokinetic properties,safety,and clinical trials of oxazolidinone drugs.
NETL
NSTL
万方数据
