产吲哚金黄杆菌感染患者的临床特征及耐药分析
Clinical characteristics and drug resistance analysis with Chrysobacterium indoleogens infection
郭琴琴 1续超 1伏慧 2李刚 2贾伟2
作者信息
- 1. 宁夏医科大学第一临床医学院,银川 750001;宁夏病原微生物重点实验室,银川 750004
- 2. 宁夏病原微生物重点实验室,银川 750004;宁夏医科大学总医院医学实验中心,银川 750004
- 折叠
摘要
目的 分析本院送检标本培养出产吲哚金黄杆菌患者的临床特征及药物敏感情况,为产吲哚金黄杆菌临床治疗提供科学依据.方法 收集我院2016年1月-2022年12月收治的36例产吲哚金黄杆菌,分析感染患者的临床特征、细菌学特征及药敏情况,并进行统计学分析.结果 36例患者中,有94.4％的人在送检前使用过广谱抗生素,50％的人进行过有创性操作.产吲哚金黄杆菌从呼吸道标本中分离最多为38.9％.药敏试验显示该菌对复方磺胺甲恶唑的敏感性最高(88.9％),对其他抗生素的敏感性分别为左氧氟沙星(69.5％)、环丙沙星(50％)、哌拉西林/他唑巴坦(47.2％),对其他抗菌药物(40.0％)以下.结论 产吲哚金黄杆菌为多重耐药菌株,主要引起呼吸道感染,尤其常见于有基础疾病及长期使用广谱抗生素的患者中,临床应密切关注.
Abstract
Objective To analyze the clinical characteristics and drug susceptibility of patients with Chrysobacterium indoleogens cultured in our hospital for examination,and to provide scientific basis for the clinical treatment of Chrysobacterium indoleogens.Methods The clinical characteristics,bacteriological characteristics and drug susceptibility of 36 patients with Chrysobacterium indoleogens infection admitted to our hospital from January 2016 to December 2022 were statistically analyzed.Results Among the 36 patients,94.4％had used broad-spectrum antibiotics before examination,and 50％had undergone invasive operation.Chrysobacterium indoleogens was isolated from respiratory specimens up to 38.9％.Drug susceptibility test found that the bacteria had the highest sensitivity to methoxybenzidine/sulfamethoxazole(88.9％),and the sensitivity to other antibiotics was levofloxacin(69.5％),ciprofloxacin(50％),piperacillin/tazobactam(47.2％),and other antibacterial drugs(40.0％).Conclusion Chrysobacterium indoligenes isolated from our hospital is a multidrug-resistant strain,which mainly causes respiratory tract infections,especially in patients with underlying diseases and long-term use of broad-spectrum antibiotics.
关键词
产吲哚金黄杆菌/耐药率/抗生素Key words
Chrysobacterium indoligenes/Drug resistance rate/Antibiotics引用本文复制引用
基金项目
宁夏回族自治区重点研发计划(2021BEG03090)
出版年
2024
NETL
NSTL
万方数据