Research progress on the blood glucose fluctuation induced by anti-infective agents
Infection is one of the most common complications of diabetes,and patients are often in need of anti-infective agents.However,anti-infective agents can induce blood glucose fluctuations,resulting in increased blood glucose management burdens for patients.In order to predict and reduce the adverse events caused by improper use of anti-infective agents,this review searched literature domestic and foreign in the past 5 years to explore the possible mechanisms and consequences of anti-infective agent-induced blood glucose fluctuations.The main reasons for blood glucose fluctuation caused by anti-infective agents include drug-drug interactions between anti-infective agents and hypoglycemic agents and damage to the islets of healthy people,which block the normal function of islet cells.Besides,the elderly and renal insufficiency patients are at high risk of inexplicable abnormal blood glucose fluctuations and other complications.In summary,it was recommended to standardize the use of anti-infective agents in clinical practice and employ appropriate anti-infective agents within appropriate courses of treatment.For the elderly and special patients with renal insufficiency,blood glucose levels should be closely monitored,and medication schedules should be adjusted in time to reduce the adverse consequences of blood glucose fluctuations caused by anti-infective agents.
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