Objective To investigate the clinical efficacy of mechanical thrombectomy for patients with acute basilar artery occlusion.Methods The clinical data of 16 patients with acute basilar artery occlusion treated by mechanical thrombectomy from January 2021 to October 2022 were retrospectively analyzed.The arterial recanalization after thrombectomy was evaluated according to the TICI grade,the neurological function was evaluated using the National Institutes of Health Stroke Scale(NIHSS)score,and the prognosis was evaluated using the modified Rankin Scale(mRS)score 90 days after surgery.Results All 16 patients were treated with TrevoProVue thrombectomy stent.TICI grade 3 was achieved in 14 patients and grade 2b in 2,and the vascular recanalization rate was 100%.The NIHSS score at discharge[(26.06±11.48)points]was significantly lower than that[(31.89±7.08)points]at admission(P<0.05).A mRS score of 0~2 was achieved in 4 patients(25%)and a mRS score of 3~5 in 12 patients,of whom 5 died within 7 days after surgery.Conclusions The mortality and disability rates of acute basilar artery occlusion are very high.Mechanical thrombectomy is a safe and effective treatment method,but there are many prognostic factors,and the prognosis of patients still needs to be improved.