颅内破裂动脉瘤栓塞术后并发吉兰-巴雷综合征1例
A case of Guillain-Barré syndrome after embolization of ruptured intracranial aneurysm
洪小康 1武倡臣 2黄新源 2关锋 2王凡2
作者信息
- 1. 550001 贵阳,贵州医科大学临床医学院
- 2. 550014 贵阳,贵州医科大学附属白云医院神经外科
- 折叠
摘要
吉兰-巴雷综合征(GBS)是一种自身免疫性神经疾病,主要特征是四肢无力和肌张力减低.颅内破裂动脉瘤栓塞术后出现肢体肌力下降一般认为是症状性血管痉挛,通常发生在术后4～10 d.本文报道1例55岁男性左侧颈内动脉C6段破裂动脉瘤,血管内栓塞术后12d突然出现渐进性四肢无力,四肢肌张力减低、腱反射消失,完善神经传导检查、脑脊液病毒抗体、血清周围神经抗体检查等检查确诊GBS.予以免疫球蛋白治疗后康复出院,7个月随访恢复正常.这提示颅内破裂动脉瘤栓塞术后脑血管痉挛期出现无明确病因的四肢肌力减退时,应当考虑到GBS,早期诊断对于避免延误病情和及时治疗非常重要.
Abstract
Guillain-Barré syndrome(GBS)is an autoimmune neurological disorder characterized by weakness and decreased muscle tone in the limbs.The decrease in limb muscle strength that occurs after endovascular embolization for ruptured intracranial aneurysms is generally considered symptomatic vasospasm,usually occurring 4～10 days after surgery.This article reports a case of a 55-year-old male with a ruptured aneurysm at the C6 segment of the left internal carotid artery who suddenly developed progressive limb weakness,decreased muscle tone in all limbs,and absent tendon reflexes 12 days after endovascular embolization.The diagnosis of GBS was confirmed by comprehensive neurological examinations,cerebrospinal fluid viral antibody testing,and serum peripheral nerve antibody testing.The patient recovered and was discharged after receiving immunoglobulin therapy,and normal recovery was observed during a 7-month follow-up.This suggests that when limb muscle weakness without a clear cause occurs during the cerebral vasospasm period after endovascular embolization of ruptured intracranial aneurysms,GBS should be considered,and early diagnosis is crucial for preventing the delay of the disease's diagnosis and enabling timely treatment.
关键词
颅内破裂动脉瘤/血管内栓塞/吉兰-巴雷综合征Key words
Ruptured intracranial aneurysms/Endovascular embolization/Guillain-Barré syndrome引用本文复制引用
出版年
2024
NETL
NSTL
万方数据