颅骨原发性弥漫性大B细胞淋巴瘤3例诊治分析并文献复习
Diagnosis and treatment of primary diffuse large B-cell lymphomas of the skull:report of 3 cases and literature review
旷仁钊 1段劼 1冯凌 1王远传1
作者信息
- 1. 637000 四川南充,川北医学院附属医院神经外科
- 折叠
摘要
目的 探讨颅骨原发性弥漫性大B细胞淋巴瘤(DLBCL)的临床特点、治疗及预后.方法 回顾性分析我院收治的3例颅骨原发性DLBCL的临床资料,并结合相关文献分析.结果 2例行颅骨肿瘤切除术,其中1例术后行化疗,另1例未行放化疗;1例活检后行放化疗.术后病理均为DLBCL.3例术后随访1～5年,1例术后化疗5年无病生存,1例活检术后放化疗2年无肿瘤复发,1例仅行手术后16个月肿瘤复发而死亡.结论 颅骨原发性DLBCL主要采取手术切除或活检术联合术后放化疗的综合治疗,术后行放化疗,预后较好;术后未行放化疗者,预后差.
Abstract
Objective To investigate the clinical features,treatment and prognosis of primary diffuse large B-cell lymphomas of the skull(DLBCL).Methods The clinical data of 3 cases of primary DLBCL of the skull treated in our hospital were retrospectively analyzed,and the relevant literatures were reviewed.Results Two patients underwent tumor resection,one of whom received chemotherapy after the operation,and the other one did not receive radiotherapy or chemotherapy.One patient underwent chemoradiotherapy after biopsy.All postoperative pathologies were DLBCL.Three patients were followed up for 1～5 years after the surgery.One patient received postoperative chemotherapy and was disease-free for 5 years,one patient received radiotherapy and chemotherapy after the biopsy and had no tumor recurrence for 2 years,and one patient only received surgery and died of tumor recurrence 16 months after the surgery.Conclusions Primary DLBCL of the skull is mainly treated by a combination of surgical resection or biopsy combined with postoperative chemoradiotherapy.Patients who receive postoperative chemoradiotherapy have a better prognosis,while those who do not receive postoperative chemoradiotherapy have a poor prognosis.
关键词
颅骨原发性肿瘤/弥漫性大B细胞淋巴瘤/临床特点/治疗/预后Key words
Primary tumor of the skull/Diffuse large B-cell lymphomas/Clinical characteristics/Treatment/Prognosis引用本文复制引用
出版年
2024
NETL
NSTL
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