Objective To investigate the feasibility and effectiveness of the"two-line intersection"approach in determining the burr hole before lateral cranial burr hole drainage.Methods Twenty volunteers with symptoms such as dizziness and headache were selected for cranial CT examinations.Prior to the CT examination,a random point was chosen on the lateral skull,and a paper clip was placed at the hair root and as close to the skin as possible;then the distances from the bottom of the small U-shaped structure in the paper clip to the outer canthus(hole-canthus diameter)and the leading edge of the tragus(hole-ear diameter)were measured manually using a tape measure.After the CT examination,the diameters of the hole-canthus and the hole-ear were measured at the post-processing workstation.Verification method:Two cotton swabs of corresponding lengths were fabricated based on the measured values at the post-processing workstation;the two cotton swabs were then applied to the lateral cranial area of the volunteers to obtain the intersection point of the superior cranial area,and the deviation between this intersection point and the simulated drilling window was calculated.Results The diameter of the hole-canthus measured by manual tape ranged from 8.20 to 11.20 cm,with an average of(9.36±0.86)cm;the diameter of the hole-canthus measured by CT system ranged from 8.10 to 11.40 cm,with an average of(9.39±0.90)cm;there was no significant difference in the diameter of the hole-canthus measured by the manual tape and the CT system(P=0.516).The hole-ear diameter measured by manual tape ranged from 7.30 to 9.30 cm,with an average of(8.50±0.53)cm;the diameter of the hole-ear measured by CT system ranged from 7.60 to 9.40 cm,with an average of(8.51±0.51)cm;there was no significant difference in the diameter of the hole-ear measured by the manual tape and the CT system(P=0.920).Verification results:The deviation between the intersection point of the two cotton swabs and the actual simulated drilling window ranged from 0 to 0.40 cm,with an average of(0.18±0.11)cm.Conclusion The application of the"two-line intersection"for locating the lateral cranial drilling window is convenient and accurate,and can provide a reference for clinical practice.