Objective To investigate the effect of ultra-early rehabilitation on postoperative recovery of patients with lumbar disc herniation(LDH)treated by TESSYS-ISEE technique.Methods Thirty-six patients with LDH,who were treated with TESSYS-ISEE technique,were prospectively recruited from July 2018 to July 2019.Among them,18 patients received ultra-early(within 8 h)postoperative rehabilitation(observation group),and 18 patients received conventional(24 h after operation)rehabilitation(control group).Visual analogue scale(VAS)was used to evaluate the lumbar and leg pain,and Barthel index was used to evaluate the curative effect.Results One patient of the observation group was re-operated due to nerve paralysis after operation,and the other 35 patients showed no obvious lumbar instability,no complications such as peripheral root canal hematoma and nerve root paralysis.The VAS score and Barthel index in the observation group were significantly better than those in the control group 24 h after operation(P<0.05),but there were no significant differences in VAS score and Barthel index between the two groups six months after surgery(P>0.05).Conclusions TESSYS-ISEE technique can reduce the early postoperative pain and facilitate the recovery of patients with LDH.