Application of autologous tissue suture technique for sellar floor reconstruction for cerebrospinal fluid leakage in patients with pituitary adenoma after transsphenoidal neuroendoscopic resection via transsphenoidal approach
Application of autologous tissue suture technique for sellar floor reconstruction for cerebrospinal fluid leakage in patients with pituitary adenoma after transsphenoidal neuroendoscopic resection via transsphenoidal approach
Objective To explore the safety and efficacy of autologous tissue suture technique for the sellar floor reconstruction for cerebrospinal fluid leakage in patients with pituitary adenoma after neuroendoscopic resection via transsphenoidal approach.Methods The clinical data of 21 patients with pituitary adenoma resected by neuroendoscopic transsphenoidal surgery via transsphenoidal approach from January 2021 to December 2023 were retrospectively analyzed.Results Cerebrospinal fluid leakage occurred in all 21 patients after opening the sellar diaphragm during the operation.The sellar floor was reconstructed by autologous tissue suture technique,and no cerebrospinal fluid rhinorrhea occurred after the operation.Two patients developed secondary intracranial infection after the operation,with an infection rate of 9.5％;one patient had epistaxis within one month after the operation.The postoperative follow-up period was 3～21 months,with an average of (9.3±6.6) months,and no cerebrospinal fluid rhinorrhea was observed.Conclusion For cerebrospinal fluid leakage caused by opening the sellar diaphragm during neuroendoscopic transsphenoidal resection of pituitary adenoma,the use of autologous tissue repair and suture technique for sellar floor reconstruction during the operation can effectively prevent postoperative cerebrospinal fluid rhinorrhea,and the surgical safety is good.
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