摘要
脊髓损伤(SCI)是由于各种原因引起脊髓结构和功能的损伤,造成损伤水平以下脊髓功能(运动、感觉、反射等)的障碍.SCI病人经常感到疼痛,发生率在26％～96％,超过1/3的病人的疼痛严重.除了恢复膀胱、肠道和运动功能外,减轻伴随的疼痛对于改善SCI病人的生活质量同样重要.脊髓刺激(SCS)是治疗慢性神经性疼痛的有效手段.然而SCS治疗SCI后疼痛的效果及作用机制尚不完全清楚.本文旨在概述SCI后疼痛以及SCS的治疗潜力.
Abstract
Spinal cord injury (SCI) refers to the damage to the structure and function of the spinal cord due to various causes,leading to disorders of spinal cord functions (such as movement,sensation,reflex,etc.) below the injury level.SCI patients often experience pain,with an incidence ranging from 26％ to 96％,and the pain is severe in more than one-third of the patients.Besides restoring bladder,intestinal,and motor functions,alleviating the accompanying pain is equally significant for improving the quality of life of SCI patients.Spinal cord stimulation (SCS) is an effective approach for treating chronic neuropathic pain.Nevertheless,the efficacy and mechanism of SCS in treating post-SCI pain remain incompletely clear.This article aims to summarize the pain after SCI and the therapeutic potential of SCS.
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