Effect of Dialectical Behavior Therapy and Sertraline on Adolescents with Depressive Disorder and Non-suicidal Self-injury Behavior
Objective:To compare the efficacy between dialectical behavior therapy combined with sertraline and sertra-line alone or dialectical treatment alone in adolescents with depressive disorder and non-suicidal self-injury behavior.Methods:90 adolescent depression patients with non-suicidal self-injury were recruited from our outpatient as the study subjects.They were divided into three groups.The HAMD-17 and HAMA were used to test depression and anxiety levels of patients at different time points;Ottawa self-Injury Questionnaire(OSI)and Trait Coping Style Questionnaire(TCSQ)were used to assess self-injury and coping style of patients.Results:After 12 weeks of treatment,compared with the sertraline alone or dialectical treatment alone groups,the sertraline+dialectical behavior group had lower scores in HAMD-17,HA-MA and TCSQ(negative scores),higher scores in the positive scores of TCSQ,and larger decline in the number of self-inju-ry behavior(P=0.005).Conclusion:Dialectical behavior therapy combined with sertraline could improve the ability to deal with stressful life events in adolescent depression patients.