首页|糖皮质激素治疗老年新型冠状病毒感染后反复发热的病例分析

糖皮质激素治疗老年新型冠状病毒感染后反复发热的病例分析

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目的 探讨老年新型冠状病毒感染后反复发热的临床特点和治疗方法.方法 收集4例老年新型冠状病毒感染后反复发热的病例资料,分析其临床特点和糖皮质激素治疗的疗效.结果 患者男3例,女1例,年龄82~86岁,发热时间24~37 d,其中3例肺部病变轻,1例肺部病变重.在4例患者中,2例用小剂量糖皮质激素(甲泼尼龙片初始剂量20 mg·d-1),2例初始剂量较大(甲泼尼龙40 mg·d-1),退热时间2~4 d.肺部病变轻的3例患者应用激素疗程短,为3~6周;肺部病变重的1例应用激素疗程长,为23周.结论 对老年新型冠状病毒感染后反复发热的病例,如肺部病变轻微,可试用小剂量糖皮质激素短疗程治疗;如肺部病变重,可适当增大剂量,延长疗程.
Case analysis of glucocorticoid therapy for recurrent fever after coronavirus disease 2019 infection in eldly patients
Objective To investigate the clinical characteristics and therapeutic method in the eldly patients with recurrent fever after coronavirus disease 2019(COVID-19)infection.Methods The data of 4 eldly patients with recurrent fever after COVID-19 infection was collected and their clinical characteristics and efficacy of glucocorticoid therapy were analyzed.Results Three patients were male and 1 was female,their ages were 82-86 years old,fever time was 24-37 days.Lung lesions in 3 patients were mild and 1 was severe.Low dose glucocorticoid was used in 2 cases(the initial dose of methylprednisolone tablets was 20 mg daily).The higher initial dose was used in 2 other cases(methylprednisolone,40 mg daily).The duration of fever reduction was 2-4 days.The treatment course of glucocorticoid was as short as 3-6 weeks for the 3 patients with mild lung lesions,and as long as 23 weeks for the patient with severe lung lesion.Conclusion For eldly patients with recurrent fever after COVID-19 infection,if the lung lesion was mild,a small dose of glucocorticoid and a short course of treatment may be used;if the lung lesion was severe,the dose can be increased appropriately and the course of treatment prolonged.

glucocorticoid therapycoronavirus disease 2019 infectionrecurrent fevereldly patient

邓美玉、于旭红、张令晖、陈玲

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中国人民解放军第三○五医院呼吸内科,北京 100017

中国人民解放军第三○五医院药局,北京 100017

糖皮质激素治疗 新型冠状病毒感染 反复发热 老年患者

2024

中国临床药理学杂志
中国药学会

中国临床药理学杂志

CSTPCD北大核心
影响因子:1.91
ISSN:1001-6821
年,卷(期):2024.40(1)
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