首页|基于CiteSpace对(制)何首乌的研究热点及发展趋势的可视化分析

基于CiteSpace对(制)何首乌的研究热点及发展趋势的可视化分析

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  • 国家科技期刊平台
  • NETL
  • NSTL
  • 万方数据
目的 对有关(制)何首乌中英文文献进行文献计量分析,探讨(制)何首乌的研究重点和趋势,为今后的科学研究提供依据.方法 利用中国知网、Web of Science数据库检索(制)何首乌的有关文献,并基于CiteSpace 6.1.R6软件利用文献计量学方法,对文章的发表年份、作者、作者国家、关键词等内容进行可视化分析.结果 本研究总共纳入中文文献1 131篇、英文文献386篇,共计1 517篇.近30年以来,在该领域的中文文献发文总量先上升后下滑,英文文献的发文总量则呈现波动性增长态势.发文量较高的作者为肖小河和王伽伯及其团队,该团队主要从事何首乌肝损伤机制与炮制减毒研究以及临床中药学与安全用药研究.关键词分析表明,本研究领域的研究热点和发展方向为(制)何首乌的效毒同源成分以及肝毒性机制及早期预警监测的研究.结论 (制)何首乌效毒同源化学成分的研究一直很活跃,对于效毒同源成分转换关系与机制研究以及肝毒性机制的研究将是该领域的研究重点与发展趋势.
Visual analysis of research hotspots and development trends of Polygoni Multiflori Radix(processed)based on CiteSpace
Objective This study aims to explore the research hotspots and trends of Polygoni Multiflori Radix(processed)and provide a reference for follow-up research by bibliometric visualization analysis.Methods Relevant Polygoni Multiflori Radix literatures were collected through databases such as PubMed,Web of Science and China National Knowledge Infrastructure.Use CiteSpace 6.1.R6 software to do bibliometric analysis on the number and years of articles,research fields,countries/regions,institutions,authors,keywords,co-citation references,and build visual maps.Results A total of 1 517 literatures(1 131 Chinese literatures and 386 English literatures)were searched through databases in this review.We therefore conducted a quantitative analysis of accessible literature published over the last 30 years found that a very modest upward trend in publication volume from Chinese and a notable increase in publication over the world.Among the author teams,there was some cooperation,and the author team with the most published papers cooperated more closely,such as XIAO Xiao-he and WANG Jia-bo's team.In particular reducing toxicity and increasing efficiency by processing,and the toxicity and the rationalusage of Polygoni Multiflori Radix were a main research direction for nearly ten years.Meanwhile,through the co-occurrence analysis of keywords,we constructed and visualized a keyword network to explore the hotspots and future directions of Polygoni Multiflori Radix.We clearly found that effective and toxic homologous components,molecular mechanisms and early warning surveillance of hepatotoxicity might be the next topics for Polygoni Multiflori Radix.Conclusion The research on the homologous chemical components of Polygoni Multiflori Radix(processed)has been very active.The research on the conversion relationship and mechanism of homologous components of Polygoni Multiflori Radix(processed)and the mechanism of hepatotoxicity will be the research focus and development trend in this field.

Polygoni Multiflori Radix(processed)CiteSpaceresearch hotspotsdevelopment trendvisual analysiseffect-toxicity relationship

唐芳、曲丽媛、岑柏宏、王萍、孙冬梅、许重远

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南方医科大学南方医院临床药学中心,广东广州 510515

南方医科大学国家药品监督管理局药物代谢研究与评价重点实验室及广东省新药筛选重点实验室,广东广州 510515

广东一方制药有限公司,广东佛山 528244

广东省中药配方颗粒企业重点实验室,广东佛山 528244

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(制)何首乌 CiteSpace 研究热点 发展趋势 可视化分析 效毒关系

国家工信部产业技术基础公共服务平台项目中药全产业链质量技术服务平台基金(2022)广东省医学科学技术研究项目南方医科大学南方医院临床研究专项

2022-230-221A20233192019CR015

2024

10.13699/j.cnki.1001-6821.2024.09.026

中国临床药理学杂志
中国药学会

中国临床药理学杂志

CSTPCD北大核心
影响因子：1.91
ISSN：1001-6821
年,卷(期)：2024.40(9)
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