首页|白花蛇舌草化学成分、药理作用、质量标志物预测的研究现状

白花蛇舌草化学成分、药理作用、质量标志物预测的研究现状

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白花蛇舌草是清热解毒的良药,对蛇虫咬伤、水肿、癌症等疾病具有独特的治疗疗效,临床应用广泛.但《中华人民共和国药典》却无白花蛇舌草的记载,其阐述"成分-药效-质量标志物(Q-Marker)"之间的关系无根本依据.本文从白花蛇舌草化学成分及药理作用方面进行综述,结合Q-Marker的概念,从传统功效、传统药性、化学成分的可测性等方面对白花蛇舌草Q-Marker进行预测,为其今后的临床应用、质量评价以及深入研究提供有益参考.
Research status of chemical constituents,pharmacological effects and predictive analysis of quality markers of Hedyotis diffusa
Hedyotis diffusa has unique therapeutic effects on snake and insect bites,edema,cancer and other diseases,and is widely used clinically.However,the《Chinese Pharmacopoeia》has no record of the name of the plant,and there is no fundamental basis for its elaboration of the relationship between"composition-potency-quality marker(Q-Marker)".This article reviews the chemical constituents and pharmacological effects of Hedyotis diffusa,and combined with the concept of Q-Marker.Q-Marker predictions were made in terms of traditional efficacy,traditional medicinal properties and the measurability of chemical components,in order to provide a reference for the clinical applications,quality evaluation further studies of Hedyotis diffusa in the future.

Hedyotis diffusachemical compositionpharmacological effectquality marker

王英杰、胡恢权、吴倩、邹佳美、平欲晖

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江西中医药大学药学院,江西南昌 330004

白花蛇舌草 化学成分 药理作用 质量标志物

江西省中医药标委会第一批标准化基金资助项目

2023A19

2024

中国临床药理学杂志
中国药学会

中国临床药理学杂志

CSTPCD北大核心
影响因子:1.91
ISSN:1001-6821
年,卷(期):2024.40(15)
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