Th17/Treg细胞与高血压相关性的研究现状
Research status of the relationship between Th17/Treg cells and hypertension
龚玉栓 1王倩 1魏惠平2
作者信息
- 1. 甘肃中医药大学中西医结合学院,甘肃兰州 730000
- 2. 甘肃中医药大学附属医院心血管科,甘肃兰州 730020
- 折叠
摘要
高血压作为一种常见的慢性疾病,其发病率在全球范围内逐年上升,且病理机制复杂,涉及遗传、环境、生活方式等多种因素.近年来,免疫-炎症机制在高血压发病中的作用逐渐受到关注.特别是辅助性T细胞17(Th17)和调节性T细胞(Treg),作为免疫系统中的重要组成部分,其平衡状态对高血压的影响成为研究热点.本文将对Th17/Treg与高血压相关性的研究进展进行综述,为高血压的免疫治疗和预防提供新的思路和方法.
Abstract
Hypertension is a common chronic disease,and its incidence is increasing year by year worldwide.Its pathological mechanism is complex,involving genetics,environment,lifestyle and other factors.In recent years,the role of immune-inflammatory mechanism in the pathogenesis of hypertension has gradually attracted attention.Especially T helper cell 17(Th17)and regulatory T cells(Treg),as important components of the immune system,the effect of their balance on hypertension has become a research hotspot.This article reviews the research progress of the correlation between Th17/Treg and hypertension,in order to provide new ideas and methods for the immunotherapy and prevention of hypertension.
关键词
辅助性T细胞17/调节性T细胞/高血压Key words
T helper cell 17/regulatory T cell/high blood pressure引用本文复制引用
基金项目
甘肃省自然科学基金资助项目(21JR7RA581)
甘肃省中医药管理局课题资助项目(GZKZ-2020-9)
甘肃中医药大学附属医院院内创新基金资助项目(KC2018-18)
出版年
2024
国家科技期刊平台
NSTL
万方数据