Research status of traditional Chinese medicine and its active ingredients in the treatment of prostate cancer by interfering with Wnt/β-catenin signaling pathway
Research status of traditional Chinese medicine and its active ingredients in the treatment of prostate cancer by interfering with Wnt/β-catenin signaling pathway
Traditional Chinese medicine and its active ingredients have significant advantages in treating prostate cancer(PCa),and can complement the shortcomings of Western medicine,improving the quality of life for patients.This article reviews the research progress of traditional Chinese medicine and its effective ingredients in intervening in Wnt/β-catenin pathway to treat PCa,summarizing that the main effective ingredients in traditional Chinese medicine for preventing and treating PCa through this pathway are flavonoids,terpenes,alkaloids,phenols,and other compounds;the main traditional Chinese medicine formulas include Guben Qingyuanfang,Yishen Tongpang granules,etc,and discusses the mechanisms of action of these traditional Chinese medicines and their effective ingredients in intervening in this pathway to prevent and treat PCa,in order to provide a reference for the precise treatment of PCa and the application of traditional Chinese medicine research.
关键词
前列腺癌/分泌型糖蛋白/β-连环蛋白/信号通路/中药/有效成分/研究现状
Key words
prostate cancer/Wnt/β-catenin/signaling pathway/traditional Chinese medicine/active ingredient/research status
维普
万方数据