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中药萜类化合物干预骨质疏松症的研究现状

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虽然传统的抗骨质疏松药物在预防和治疗骨质疏松症(OP)方面具有较好的效果,但在发挥药效的过程中也会出现多种药物不良反应.萜类化合物对骨吸收、骨形成以及伴随炎症具有良好的治疗作用.本文对多种常用于治疗OP的中药萜类化合物进行综述,以期为今后的临床治疗和相关基础研究提供思路.
Research status of terpenoids in traditional Chinese medicine against osteoporosis
Although conventional anti-osteoporotic drugs are effective in the prevention and treatment of osteoporosis(OP),they are also associated with a variety of adverse drug reactions in the course of their efficacy.Terpenoids have favorable therapeutic effects on bone resorption,bone formation,and concomitant inflammation.In this paper,we review a variety of herbal terpenoids commonly used in the treatment of OP,with a view to providing ideas for future clinical treatment and related basic research.

traditional Chinese medicineterpenoidsosteoporosis

程渊、张良童、谢兴文、黄委委、林德民、刘东、岳斌、周岳菡、梅镐

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甘肃中医药大学中医临床学院,甘肃兰州 730000

甘肃中医药大学附属医院老年骨科,甘肃兰州 730000

天水市卫生学校护理学院,甘肃天水 741000

中药 萜类化合物 骨质疏松症

2024

中国临床药理学杂志
中国药学会

中国临床药理学杂志

CSTPCD北大核心
影响因子:1.91
ISSN:1001-6821
年,卷(期):2024.40(21)