Research status of population pharmacokinetics of tacrolimus in patients with non-transplant diseases
Tacrolimus is the first immunosuppressive choice for organ transplantation.It is also used in the immunotherapy of many non-transplant diseases.Because of its large individual variabilities and narrow treatment window,the individualized administration for tacrolimus taking advantage of population pharmacokinetics is necessary.This article aims to summarize population pharmacokinetics studies of tacrolimus in patients with non-transplant diseases and its influencing factors,and to provide a reference for rational use of tacrolimus.
tacrolimuspopulation pharmacokineticsnon-transplant diseasespersonalized medicine
万方数据
维普
